Schoof Benjamin, Jakobs Oliver, Schmidl Stefan, Klatte Till Orla, Frommelt Lars, Gehrke Thorsten, Gebauer Matthias
Department of Orthopedic Surgery, HELIOS Endo-Clinic Hamburg , Hamburg, Germany.
Department of Trauma-, Hand- and Reconstructive Surgery, University Medical Center Hamburg-Eppendorf , Hamburg, Germany.
Orthop Rev (Pavia). 2015 Mar 31;7(1):5748. doi: 10.4081/or.2015.5748. eCollection 2015 Mar 3.
Periprosthetic joint infection (PJI) is a severe complication of total joint arthroplasty with an incidence of approximately 1%. Due to the high risk of persisting infection, successful treatment of fungal PJI is challenging. The purpose of this study was to gain insight into the current management of fungal PJI of the hip and, by systematically reviewing the cases published so far, to further improve the medical treatment of this serious complication of total hip arthroplasty. Thus, we conducted a systematic review of the available literature concerning fungal PJI in total hip arthroplasty, including 45 cases of fungal PJI. At the moment a two-stage revision procedure is favorable and there is an ongoing discussion on the therapeutic effect of antifungal drug loaded cement spacers on fungal periprosthetic infections of the hip. Due to the fact that there is rare experience with it, there is urgent need to establish guidelines for the treatment of fungal infections of total hip arthroplasty.
人工关节周围感染（PJI）是全关节置换术的一种严重并发症，发病率约为1%。由于持续感染的风险很高，真菌性人工关节周围感染的成功治疗具有挑战性。本研究的目的是深入了解目前髋部真菌性人工关节周围感染的治疗情况，并通过系统回顾迄今为止发表的病例，进一步改善这种全髋关节置换术严重并发症的医学治疗。因此，我们对全髋关节置换术中有关真菌性人工关节周围感染的现有文献进行了系统回顾，包括45例真菌性人工关节周围感染病例。目前，两阶段翻修手术是有利的，关于载有抗真菌药物的骨水泥间隔物对髋部真菌性人工关节周围感染的治疗效果也在进行讨论。由于对此经验稀少，迫切需要制定全髋关节置换术真菌感染的治疗指南。
