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表现为白细胞破碎性血管炎的支原体上呼吸道感染

Mycoplasmal upper respiratory infection presenting as leukocytoclastic vasculitis.

作者信息

Rao Mana, Agrawal Abhinav, Parikh Manan, Banayat Rikka, Thomas Maria Joana, Guo Tianhua, Lee Andrew

机构信息

Department of Internal Medicine, Monmouth Medical Center , Long Branch, NJ, USA.

Department of Pathology, Monmouth Medical Center , Long Branch, NJ, USA.

出版信息

Infect Dis Rep. 2015 Feb 24;7(1):5605. doi: 10.4081/idr.2015.5605.

DOI:10.4081/idr.2015.5605
PMID:25874067
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4387368/
Abstract

Mycoplasma is a virulent organism that is known to primarily infect the respiratory tract; however, affection of the skin, nervous system, kidneys, heart and bloodstream has been observed in various forms, which include Stevens Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, encephalitis, renal failure, conduction system abnormalities and hemolytic anemia. Small vessel vasculitis is a lesser-known complication of mycoplasma pneumonia infection. We report a case of mycoplasmal upper respiratory tract infection with striking cutaneous lesions as the presenting symptom. Mycoplasmal infection was confirmed by serology testing, skin biopsy was suggestive of leukocytoclastic vasculitis. This case brings forth an uncommon manifestation of mycoplasmal infection with extra-pulmonary affection, namely small vessel vasculitis.

摘要

支原体是一种致病性微生物,已知主要感染呼吸道;然而,也观察到其以多种形式影响皮肤、神经系统、肾脏、心脏和血液系统,这些形式包括史蒂文斯-约翰逊综合征、多形红斑、中毒性表皮坏死松解症、脑炎、肾衰竭、传导系统异常和溶血性贫血。小血管血管炎是支原体肺炎感染较少见的并发症。我们报告一例以显著皮肤损害为首发症状的支原体上呼吸道感染病例。通过血清学检测确诊为支原体感染,皮肤活检提示白细胞破碎性血管炎。该病例呈现了支原体感染伴肺外表现的一种罕见表现,即小血管血管炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1264/4387368/14cd0f00723c/idr-2015-1-5605-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1264/4387368/14cd0f00723c/idr-2015-1-5605-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1264/4387368/14cd0f00723c/idr-2015-1-5605-g001.jpg

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