Satirapoj Bancha, Tasanavipas Pamila, Supasyndh Ouppatham
Division of Nephrology, Department of Medicine, Phramongkutklao Hospital and College of Medicine, Bangkok 10400, Thailand.
Int J Nephrol. 2015;2015:857316. doi: 10.1155/2015/857316. Epub 2015 Mar 19.
A total of 244 patients with lupus nephritis (219 women (89.8%) with a female to male ratio of 9 : 1) were included in the study. Clinical and laboratory findings at renal biopsy are clinically valuable in identifying different renal classifications of lupus pathology, activity, and chronicity index. Patients with class IVG had significantly higher proportions of microscopic hematuria, proteinuria, hypertension, impaired renal function, anemia, hypoalbuminuria, and positive anti-DNA antibody. All of these findings correlated well with high activity index and chronicity index of lupus pathology. Considering these correlations may help to determine the clinicopathologic status of lupus patients.
共有244例狼疮性肾炎患者（219例女性（89.8%），男女比例为9∶1）纳入本研究。肾活检时的临床和实验室检查结果对于识别狼疮病理、活动度和慢性指数的不同肾脏分类具有临床价值。IVG级患者的镜下血尿、蛋白尿、高血压、肾功能损害、贫血、低白蛋白尿和抗DNA抗体阳性的比例显著更高。所有这些结果均与狼疮病理的高活动指数和慢性指数密切相关。考虑这些相关性可能有助于确定狼疮患者的临床病理状态。
