Przegaliński E, Siwanowicz J, Baran L
Institute of Pharmacology, Polish Academy of Sciences, Kraków.
Pol J Pharmacol Pharm. 1989 Jan-Feb;41(1):41-4.
The effect of acute and repeated (once daily for 10 days) treatment with ECS on drinking induced by isoprenaline (50 micrograms, intracerebroventricularly, icv) was studied in rats. It was found that repeated, but not acute, administration of ECS significantly reduced the behavioral response to isoprenaline.
研究了内源性大麻素系统(ECS)急性和重复(每日一次,持续10天)给药对大鼠由异丙肾上腺素(50微克,脑室内注射,icv)诱导的饮水行为的影响。结果发现,ECS重复给药而非急性给药显著降低了对异丙肾上腺素的行为反应。