Can J Gastroenterol Hepatol. 2015 Jun-Jul;29(5):253-7. doi: 10.1155/2015/967683. Epub 2015 Apr 15.
Renal impairment is common in liver disease and may occur as a consequence of the pathophysiological changes that underpin cirrhosis or secondary to a pre-existing unrelated insult. Nevertheless, the onset of renal impairment often portends a worsening prognosis. Hepatorenal syndrome remains one of the most recognized and reported causes of renal impairment in cirrhosis. However, other causes of renal impairment occur and can be classified into prerenal, intrinsic or postrenal, which are the subjects of the present review.
肾功能损害在肝病中很常见,可能是肝硬化基础的病理生理变化的结果,也可能继发于先前无关的损伤。然而,肾功能损害的发生往往预示着预后恶化。肝肾综合征仍然是肝硬化中最常见和报道的肾功能损害原因之一。但是,其他原因的肾功能损害也会发生,可以分为肾前性、肾性或肾后性,这是本次综述的主题。