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[甲状腺功能亢进和减退时血小板的脂质成分及聚集能力]

[The lipid composition and aggregating capacity of thrombocytes in hyper- and hypothyroidism].

作者信息

Saipov T D, Aripov D A, Khashimova R M, Abduzhamilov A A, Saatov T S

出版信息

Probl Endokrinol (Mosk). 1989 Sep-Oct;35(5):47-50.

PMID:2587526
Abstract

The aim of the work was to investigate the phospholipid composition and parameters of platelet aggregation in patients with hypo- and hyperthyroidism. The data obtained have shown that phospholipid liposomes added exogenously, changed the function of cell hemostasis and, in particular, decreased platelet aggregation. Unlike the other phospholipids, phosphatidylinositol, cardiolipin and phosphatidylserine produced the most significant effect on this index and corrected, to a certain extent, disturbed platelet functions in hypothyroidism.

摘要

这项工作的目的是研究甲状腺功能减退和亢进患者的磷脂组成及血小板聚集参数。获得的数据表明,外源性添加的磷脂脂质体改变了细胞止血功能,尤其是降低了血小板聚集。与其他磷脂不同,磷脂酰肌醇、心磷脂和磷脂酰丝氨酸对该指标产生了最显著的影响,并在一定程度上纠正了甲状腺功能减退症中紊乱的血小板功能。

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