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本文引用的文献

1
Bactericidal activity of pyrazinamide and clofazimine alone and in combinations with pretomanid and bedaquiline.吡嗪酰胺和氯法齐明单独及与贝达喹啉和德拉马尼联合的杀菌活性。
Am J Respir Crit Care Med. 2015 Apr 15;191(8):943-53. doi: 10.1164/rccm.201410-1801OC.
2
Clofazimine for the treatment of multidrug-resistant tuberculosis: prospective, multicenter, randomized controlled study in China.氯法齐明治疗耐多药结核病的前瞻性、多中心、随机对照研究在中国进行。
Clin Infect Dis. 2015 May 1;60(9):1361-7. doi: 10.1093/cid/civ027. Epub 2015 Jan 20.
3
Clofazimine shortens the duration of the first-line treatment regimen for experimental chemotherapy of tuberculosis.氯法齐明可缩短结核病实验性化疗一线治疗方案的疗程。
Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):869-74. doi: 10.1073/pnas.1416951112. Epub 2015 Jan 5.
4
Successful '9-month Bangladesh regimen' for multidrug-resistant tuberculosis among over 500 consecutive patients.针对500多名连续患者的耐多药结核病的成功“孟加拉国9个月治疗方案” 。
Int J Tuberc Lung Dis. 2014 Oct;18(10):1180-7. doi: 10.5588/ijtld.14.0100.
5
Randomized dose-ranging study of the 14-day early bactericidal activity of bedaquiline (TMC207) in patients with sputum microscopy smear-positive pulmonary tuberculosis.随机剂量范围研究贝达喹啉（TMC207）在痰显微镜检查涂片阳性肺结核患者中的 14 天早期杀菌活性。
Antimicrob Agents Chemother. 2013 May;57(5):2199-203. doi: 10.1128/AAC.02243-12. Epub 2013 Mar 4.
6
14-day bactericidal activity of PA-824, bedaquiline, pyrazinamide, and moxifloxacin combinations: a randomised trial.PA-824、贝达喹啉、吡嗪酰胺和莫西沙星联合治疗的 14 天杀菌活性：一项随机试验。
Lancet. 2012 Sep 15;380(9846):986-93. doi: 10.1016/S0140-6736(12)61080-0. Epub 2012 Jul 23.
7
Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals.利用抗生素产生的羟基自由基根除细菌持久期细胞。
Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12147-52. doi: 10.1073/pnas.1203735109. Epub 2012 Jul 9.
8
Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance.随机先导试验：使用贝达喹啉（TMC207）治疗 8 周治疗耐多药结核病：长期结果、耐受性和对耐药性出现的影响。
Antimicrob Agents Chemother. 2012 Jun;56(6):3271-6. doi: 10.1128/AAC.06126-11. Epub 2012 Mar 5.
9
Sterilizing activity of second-line regimens containing TMC207 in a murine model of tuberculosis.二线方案中包含 TMC207 对结核分枝杆菌感染小鼠模型的杀菌活性。
PLoS One. 2011 Mar 3;6(3):e17556. doi: 10.1371/journal.pone.0017556.
10
Reduction of clofazimine by mycobacterial type 2 NADH:quinone oxidoreductase: a pathway for the generation of bactericidal levels of reactive oxygen species.分枝杆菌型 2NADH：醌氧化还原酶还原氯法嗪：生成杀菌水平活性氧的途径。
J Biol Chem. 2011 Mar 25;286(12):10276-87. doi: 10.1074/jbc.M110.200501. Epub 2010 Dec 30.

A reader's guide to the bactericidal activity of pyrazinamide and clofazimine alone and in combinations with pretomanid and bedaquiline.

作者信息

Grosset Jacques, Vernon Andrew

机构信息

1 Center for Tuberculosis Research Johns Hopkins University School of Medicine Baltimore, Maryland.

出版信息

Am J Respir Crit Care Med. 2015 Apr 15;191(8):871-3. doi: 10.1164/rccm.201502-0367ED.

DOI:10.1164/rccm.201502-0367ED
PMID:25876201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5884099/
Abstract
摘要