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非声学因素在体外空化活动诱导与增殖中的作用。

The role of non-acoustic factors in the induction and proliferation of cavitational activity in vitro.

作者信息

Williams A R, Miller D L

机构信息

Department of Medical Biophysics, University of Manchester Medical School, UK.

出版信息

Phys Med Biol. 1989 Nov;34(11):1561-9. doi: 10.1088/0031-9155/34/11/005.

DOI:10.1088/0031-9155/34/11/005
PMID:2587627
Abstract

It is well known that a liquid exposed to relatively low intensities of MHz ultrasound may or may not cavitate depending upon a variety of non-acoustic factors. This paper shows that in some cases the material used as the acoustically transparent window and even the length of the sample chamber may also be important factors. Cling film, dialysis membrane and Parafilm are all equally acceptable as acoustically transparent windows for ultrasound, whereas glass cover slips or 'soft' surfaces (in which active bubbles may embed themselves) are not. All the results obtained confirm the validity of bubble recycling as being the dominant mechanism responsible for the enhancement of cavitational activity commonly observed when the sample chamber is rotated.

摘要

众所周知,暴露于相对低强度兆赫兹超声下的液体可能会发生空化,也可能不会,这取决于多种非声学因素。本文表明,在某些情况下,用作声学透明窗口的材料甚至样品腔的长度也可能是重要因素。保鲜膜、透析膜和石蜡膜作为超声的声学透明窗口都是同样可接受的,而玻璃盖玻片或“软”表面(活性气泡可能嵌入其中)则不行。所有获得的结果都证实了气泡循环作为主要机制的有效性,该机制是样品腔旋转时通常观察到的空化活性增强的原因。

相似文献

1
The role of non-acoustic factors in the induction and proliferation of cavitational activity in vitro.非声学因素在体外空化活动诱导与增殖中的作用。
Phys Med Biol. 1989 Nov;34(11):1561-9. doi: 10.1088/0031-9155/34/11/005.
2
Mechanisms for hemolysis by ultrasonic cavitation in the rotating exposure system.
Ultrasound Med Biol. 1991;17(2):171-8. doi: 10.1016/0301-5629(91)90124-f.
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Bubble cycling as the explanation of the promotion of ultrasonic cavitation in a rotating tube exposure system.
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Hemolysis of 40% hematocrit, Albunex-supplemented human erythrocytes by pulsed ultrasound: frequency, acoustic pressure and pulse length dependence.
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Damage to red blood cells induced by acoustic cavitation.声空化诱导的红细胞损伤。
Ultrasound Med Biol. 1995;21(1):105-11. doi: 10.1016/0301-5629(94)00089-1.
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Ultrasonically induced hemolysis at high cell and gas body concentrations in a thin-disc exposure chamber.在薄盘暴露室中,高细胞和气体浓度下的超声诱导溶血。
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Hemolysis of albunex-supplemented, 40% hematocrit human erythrocytes in vitro by 1-MHz pulsed ultrasound: acoustic pressure and pulse length dependence.1兆赫兹脉冲超声对补充了白蛋白微球、血细胞比容为40%的人红细胞的体外溶血作用:声压和脉冲长度依赖性
Ultrasound Med Biol. 1996;22(7):927-38. doi: 10.1016/0301-5629(96)00108-1.
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Nucleation and evolution of ultrasonic cavitation in a rotating exposure chamber.
J Ultrasound Med. 1992 Aug;11(8):407-12. doi: 10.7863/jum.1992.11.8.407.
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Photometric detection of ATP release from human erythrocytes exposed to ultrasonically activated gas-filled pores.光度法检测暴露于超声激活充气孔隙的人红细胞中ATP的释放。
Ultrasound Med Biol. 1980;6(3):251-6. doi: 10.1016/0301-5629(80)90020-4.
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Acoustic cavitation: a possible consequence of biomedical uses of ultrasound.声空化:超声在生物医学应用中可能产生的后果。
Br J Cancer Suppl. 1982 Mar;5:140-6.

引用本文的文献

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Ultrasound Med Biol. 2013 Apr;39(4):611-9. doi: 10.1016/j.ultrasmedbio.2012.11.026. Epub 2013 Feb 13.
2
Section 8--clinical relevance. American Institute of Ultrasound in Medicine.第8节——临床相关性。美国医学超声学会。
J Ultrasound Med. 2000 Feb;19(2):149-68. doi: 10.7863/jum.2000.19.2.149.
3
Section 7--discussion of the mechanical index and other exposure parameters. American Institute of Ultrasound in Medicine.
第7节——机械指数及其他暴露参数的讨论。美国医学超声学会。
J Ultrasound Med. 2000 Feb;19(2):143-8, 154-68. doi: 10.7863/jum.2000.19.2.143.
4
Section 6--mechanical bioeffects in the presence of gas-carrier ultrasound contrast agents. American Institute of Ultrasound in Medicine.第6节——气体载体超声造影剂存在下的机械生物效应。美国超声医学学会。
J Ultrasound Med. 2000 Feb;19(2):120-42, 154-68. doi: 10.7863/jum.2000.19.2.120.
5
Section 4--bioeffects in tissues with gas bodies. American Institute of Ultrasound in Medicine.第4节——含气体组织中的生物效应。美国医学超声学会。
J Ultrasound Med. 2000 Feb;19(2):97-108, 154-68. doi: 10.7863/jum.2000.19.2.97.
6
Bacterial stress responses to 1-megahertz pulsed ultrasound in the presence of microbubbles.在存在微泡的情况下,细菌对1兆赫兹脉冲超声的应激反应。
Appl Environ Microbiol. 1998 Oct;64(10):3927-31. doi: 10.1128/AEM.64.10.3927-3931.1998.