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非结核分枝杆菌肺病伴机化性肺炎

Nontuberculous mycobacterial lung disease accompanied by organizing pneumonia.

作者信息

Nakahara Yasuharu, Oonishi Yasutaka, Takiguchi Junji, Morimoto Akie, Matsuoka Katsunari, Imanishi Naoko, Higashino Takanori, Mimura Rokuro, Kawamura Tetsuji, Mochiduki Yoshiro

机构信息

Department of Respiratory Medicine, National Hospital Organization Himeji Medical Center, Japan.

出版信息

Intern Med. 2015;54(8):945-51. doi: 10.2169/internalmedicine.54.3616. Epub 2015 Apr 15.

Abstract

We herein report our experience with patients who had nontuberculous mycobacterial lung disease (NTM disease) accompanied by organizing pneumonia (OP). Out of 98 NTM disease patients who had undergone a biopsy or surgical resection, 11 patients had OP that was revealed histologically. After excluding six patients who had OP-related diseases (idiopathic interstitial pneumonia, rheumatoid arthritis, etc.), the remaining five patients were studied. Two of them (a 73-year-old man and a 66-year-old woman) showed common clinical feature: acute-onset symptoms of cough and fever, infiltrating shadows and dramatic improvement following treatment with a corticosteroid and anti-mycobacterial therapy. Our cases demonstrate that NTM disease is sometimes accompanied by OP histologically, and some such cases show common clinical features.

摘要

我们在此报告我们对患有非结核分枝杆菌肺病(NTM病)并伴有机化性肺炎(OP)患者的经验。在98例接受活检或手术切除的NTM病患者中,有11例经组织学检查发现患有OP。在排除6例患有OP相关疾病(特发性间质性肺炎、类风湿性关节炎等)的患者后,对其余5例患者进行了研究。其中2例(1名73岁男性和1名66岁女性)表现出共同的临床特征:咳嗽和发热的急性发作症状、浸润阴影以及在接受皮质类固醇和抗分枝杆菌治疗后病情显著改善。我们的病例表明,NTM病有时在组织学上伴有OP,并且一些此类病例表现出共同的临床特征。

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