Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, 180 Feng Lin Road, Shanghai, 200032, PR China.
BMC Infect Dis. 2010 Mar 11;10:64. doi: 10.1186/1471-2334-10-64.
The association of Kikuchi Fujimoto disease (KFD) with cryptogenic organizing pneumonia (COP) is extremely rare. We report a case of simultaneous diagnosis of KFD and COP.
A 33-year-old male presented with a 1-month cough illness and fever lasting for 5 days. The chest radiograph revealed double lower lobe infiltrate, which was unresponsive to antibiotics. A cervical lymph node was first found in the development of this disease. Bronchoscopy, bronchoalveolar lavage and lung biopsy established the diagnosis of COP, while a lymph node biopsy was consistent with KFD. The patient improved on steroids.
KFD and COP are possible part of a disease continuum, rather than separate entities.
Kikuchi Fujimoto 病（KFD）与隐源性机化性肺炎（COP）的关联极为罕见。我们报告了一例同时诊断 KFD 和 COP 的病例。
一名 33 岁男性因 1 个月的咳嗽病和持续 5 天的发热就诊。胸部 X 线片显示双下叶浸润，对抗生素无反应。该病发展过程中首先发现颈部淋巴结。支气管镜检查、肺泡灌洗和肺活检确立了 COP 的诊断，而淋巴结活检与 KFD 一致。患者在类固醇治疗后好转。
KFD 和 COP 可能是同一疾病连续体的一部分，而不是独立的实体。
