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副乳腺癌的临床病理分析:22例报告

[Clinicopathological analyses of accessory breast cancer: a report of 22 cases].

作者信息

Wang Haotian, Duan Jingjing, Xin Fei, Cao Xuchen

机构信息

Center of Breast Cancer, Cancer Institute & Hospital, Tianjin Medical University, Tianjin 300060, China.

Center of Breast Cancer, Cancer Institute & Hospital, Tianjin Medical University, Tianjin 300060, China. Email:

出版信息

Zhonghua Yi Xue Za Zhi. 2015 Jan 27;95(4):260-3.

Abstract

OBJECTIVE

To explore the clinicopathological characteristics, diagnosis, multi-disciplinary therapy and prognosis of accessory breast cancer.

METHODS

The clinical data were retrospectively analyzed for 22 patients with accessory breast cancer from December 2000 and September 2013.

RESULTS

Three patients underwent breast-conserving local wide excision of tumor plus axillary lymph node dissection while the remainder had Auchincloss or Halsted mastectomy. The most common histological type was infiltrating ductal carcinoma (n = 16, 72%) and one of them was associated with mucous adenocarcinoma. There were carcinoma simplex (n = 1), papillary adenocarcinoma (n = 1) and adenocarcinoma (n = 4). The most common pathological stages (according to AJCC Staging of Breast Cancer, 2002, 6th edition) were II (n = 15, 68%),I(n = 3), III (n = 4) and IV (n = 0). The median follow-up period was 3 (1-14) years. And the follow-up rate was 100%.Until October 2014, 2 patients died from metastasis and the remainder survived.

CONCLUSIONS

Accessory breast cancer is rare and has a worse prognosis.Now the clinical diagnostic criteria to it remains controversial and the diagnosis is often late. A definite diagnosis is made on the basis of clinical characteristics, postoperative pathology and imaging examinations. And surgery remains a major option.

摘要

目的

探讨副乳腺癌的临床病理特征、诊断、多学科治疗及预后。

方法

回顾性分析2000年12月至2013年9月期间22例副乳腺癌患者的临床资料。

结果

3例患者行保乳局部广泛肿瘤切除加腋窝淋巴结清扫术,其余患者行Auchincloss或Halsted乳房切除术。最常见的组织学类型为浸润性导管癌(n = 16,72%),其中1例合并黏液腺癌。还有单纯癌(n = 1)、乳头状腺癌(n = 1)和腺癌(n = 4)。最常见的病理分期(根据2002年美国癌症联合委员会第6版乳腺癌分期)为Ⅱ期(n = 15,68%)、Ⅰ期(n = 3)、Ⅲ期(n = 4)和Ⅳ期(n = 0)。中位随访时间为3(1 - 14)年,随访率为100%。截至2014年10月,2例患者死于转移,其余患者存活。

结论

副乳腺癌罕见,预后较差。目前其临床诊断标准仍存在争议,且诊断往往较晚。需根据临床特征、术后病理及影像学检查做出明确诊断。手术仍是主要的治疗选择。

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