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腹壁男性副乳腺癌:一例报告及文献复习

Male accessory breast cancer on the abdominal wall: a case report and literature review.

作者信息

Zhong Guo-Bin, Ye Xin-Qing, Liu Jian-Lun, Xiao Shu-Zhe, Huang Qing-Hua, Wei Wei

机构信息

Department of Breast Surgery, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China,

Department of Pathology, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China.

出版信息

Onco Targets Ther. 2018 Oct 8;11:6625-6631. doi: 10.2147/OTT.S184185. eCollection 2018.

Abstract

BACKGROUND

Accessory breast cancer is very rare, particularly in men. Male accessory breast cancer on the abdominal wall has not been documented in the scientific literature so far. We describe a case of male accessory breast cancer on the abdominal wall.

CASE PRESENTATION

We describe a male patient suffering a swelling and erosive, enlarged, and hardened abdominal wall mass with pain due to abdominal wall accessory breast cancer. The patient had no obvious disease history, and the initial clinical symptom was a small mass on the abdominal wall. B-ultrasound revealed a solid subcutaneous nodule in the right abdomen with a size of ~2.8 × 2.5 × 1.5 cm. The abdominal wall tumor resection was performed with local anesthesia. Pathological testing revealed a grade II infiltrating ductal carcinoma derived from the accessory mammary gland (right abdominal wall) with neuroendocrine characteristics, showing ER (100% strong positive), PR (100% strong positive), HER-2 (-), ki67 (40% positive), Syn (+), CgA (+), and GCDFP15 (+).

CONCLUSION

Nonaxillary accessory breast cancer in males is very rare, with no obvious clinical manifestations, and could be easily ignored. This disease requires great attention from clinicians.

摘要

背景

副乳腺癌非常罕见,在男性中尤为如此。迄今为止,科学文献中尚未记载男性腹壁副乳腺癌。我们报告一例男性腹壁副乳腺癌病例。

病例介绍

我们描述了一名男性患者,因腹壁副乳腺癌出现肿胀、糜烂、增大且变硬的腹壁肿块并伴有疼痛。患者无明显病史,最初的临床症状是腹壁上的一个小肿块。B超显示右下腹有一个实性皮下结节,大小约为2.8×2.5×1.5厘米。在局部麻醉下进行了腹壁肿瘤切除术。病理检查显示为源自副乳腺(右腹壁)的II级浸润性导管癌,具有神经内分泌特征,显示雌激素受体(ER,100%强阳性)、孕激素受体(PR,100%强阳性)、人表皮生长因子受体2(HER-2,阴性)、增殖细胞核抗原(ki67,40%阳性)、突触素(Syn,阳性)、嗜铬粒蛋白A(CgA,阳性)和乳腺珠蛋白15(GCDFP15,阳性)。

结论

男性非腋窝副乳腺癌非常罕见,无明显临床表现,容易被忽视。这种疾病需要临床医生高度关注。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/352c/6188187/87b633b4b735/ott-11-6625Fig1.jpg

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