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通过β-环糊精使2,2-二苯基-1-苦基肼基自由基在水中溶解,以评估抗氧化剂在水介质中的自由基清除活性。

Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media.

作者信息

Nakanishi Ikuo, Ohkubo Kei, Imai Kohei, Kamibayashi Masato, Yoshihashi Yasuo, Matsumoto Ken-ichiro, Fukuhara Kiyoshi, Terada Katsuhide, Itoh Shinobu, Ozawa Toshihiko, Fukuzumi Shunichi

机构信息

Radio-Redox-Response Research Team, Advanced Particle Radiation Biology Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences (NIRS), Inage-ku, Chiba 263-8555, Japan.

出版信息

Chem Commun (Camb). 2015 May 14;51(39):8311-4. doi: 10.1039/c5cc02236c.

DOI:10.1039/c5cc02236c
PMID:25877460
Abstract

A 2,2-diphenyl-1-picrylhydrazyl radical (DPPH˙) was successfully solubilised in water by β-cyclodextrin (β-CD). DPPH˙/β-CD thus obtained was demonstrated to be a powerful tool to evaluate the antioxidative activity of water-soluble antioxidants, such as ascorbate and Trolox, in aqueous buffer solutions.

摘要

2,2-二苯基-1-苦基肼自由基(DPPH˙)通过β-环糊精(β-CD)成功溶解于水中。由此获得的DPPH˙/β-CD被证明是评估水溶性抗氧化剂(如抗坏血酸盐和Trolox)在水性缓冲溶液中抗氧化活性的有力工具。

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