中等高剂量葡萄糖酸锌或甘氨酸锌：对年轻成年女性血浆锌和红细胞超氧化物歧化酶活性的影响。

Moderately High Dose Zinc Gluconate or Zinc Glycinate: Effects on Plasma Zinc and Erythrocyte Superoxide Dismutase Activities in Young Adult Women.

作者信息

DiSilvestro Robert A, Koch Erin, Rakes Linda

机构信息

Human Nutrition, Ohio State University, 345 Campbell Hall, 1787 Neil Ave, Columbus, OH, 43210, USA.

出版信息

Biol Trace Elem Res. 2015 Nov;168(1):11-4. doi: 10.1007/s12011-015-0334-3. Epub 2015 Apr 17.

DOI:10.1007/s12011-015-0334-3

PMID:25877802

Abstract

Some zinc (Zn) research studies have used either Zn gluconate or Zn glycinate, but the two forms have not been compared much. Therefore, a moderately high dose of the two forms (60 mg Zn/day) were compared in a 6-week intervention in young adult women. Plasma Zn, the traditional assessment of Zn status, was increased in all subjects given Zn glycinate (N = 10), while no significant change was seen overall for Zn gluconate or placebo (N = 10 each). Erythrocyte superoxide dismutase activity, a marker for Zn-induced copper deficiency, was unchanged in all three groups. Thus, for the conditions of this study, Zn glycinate effectively changed Zn status better than Zn gluconate, but neither impacted copper status.

摘要

一些锌（Zn）的研究使用了葡萄糖酸锌或甘氨酸锌，但这两种形式的比较并不多。因此，在一项针对年轻成年女性的为期6周的干预研究中，对这两种形式的中等高剂量（60毫克锌/天）进行了比较。血浆锌是评估锌状态的传统指标，在所有服用甘氨酸锌的受试者（N = 10）中均有所增加，而服用葡萄糖酸锌或安慰剂的受试者（每组N = 10）总体上没有显著变化。红细胞超氧化物歧化酶活性是锌诱导铜缺乏的一个指标，在所有三组中均未改变。因此，在本研究条件下，甘氨酸锌比葡萄糖酸锌更有效地改变了锌状态，但两者均未影响铜状态。