Zeng Yingchun, Cui Ying, Li Jie
Department of Obstetrics, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Department of Psychiatry, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
BMC Psychiatry. 2015 Apr 2;15:66. doi: 10.1186/s12888-015-0452-7.
Depression during pregnancy can be detrimental to both maternal and fetal health outcomes. A cross-sectional study was undertaken, with the goal of determining the prevalence and predicting factors associated with antenatal depressive symptoms during late pregnancy among Chinese women.
Participants were recruited during bookings for antenatal care at a maternal and child health hospital's outpatient care clinics. Measurements included the Chinese version of Self-rating Depression Scale, Eysenck Personality Questionnaire, Social Support Rating Scale, and Simplified Coping Strategies Questionnaire.
A total of 292 women participated in this study, with 28.5% prevalence of depressive symptoms. Significant protective predictors were: a younger age (OR = 0.85; 95% Confidence Interval-CI 0.76-0.95), good partner relationship (OR = 0.40; 95% CI 0.17-0.93), preparedness for delivery (OR = 0.36; 95% CI 0.20-0.63), active coping (OR = 0.92; 95% CI 0.89-0.96), and social support (OR = 0.92; 95% CI 0.88-0.97). In contrast, significant risk factors were: a history of miscarriage (OR = 1.86; 95% CI 1.30-2.66), irregular menstrual history (OR = 2.98; 95% CI 1.64-5.40), and financial worries (OR = 2.33; 95% CI 1.27-4.30). Psychosocial risk factors include psychoticism and neuroticism personality traits (OR = 1.06; 95% CI 1.02-1.10 and OR = 1.07; 95% CI 1.04-1.10, respectively), and pregnancy pressures (OR = 1.04; 95% CI 1.02-1.07).
Depressive symptoms are common in third trimester antenatal clinic attendees. Interventions for early recognition of depression should target older women with a history of miscarriage and financial worries. Intervention strategies could be by providing more social support and promoting active coping strategies. Findings support a recommendation that antenatal services consider integrating screening for depression in routine antenatal care.
孕期抑郁可能对母婴健康结局都产生不利影响。开展了一项横断面研究，目的是确定中国女性妊娠晚期产前抑郁症状的患病率及相关预测因素。
在一家妇幼保健院门诊进行产前检查预约时招募参与者。测量工具包括中文版自评抑郁量表、艾森克人格问卷、社会支持评定量表和简易应对方式问卷。
共有292名女性参与本研究，抑郁症状患病率为28.5%。显著的保护因素为：年龄较小（比值比[OR]=0.85；95%置信区间[CI]0.76 - 0.95）、伴侣关系良好（OR = 0.40；95% CI 0.17 - 0.93）、分娩准备（OR = 0.36；95% CI 0.20 - 0.63）、积极应对（OR = 0.92；95% CI 0.89 - 0.96）和社会支持（OR = 0.92；95% CI 0.88 - 0.97）。相反，显著的危险因素为：流产史（OR = 1.86；95% CI 1.30 - 2.66）、月经史不规律（OR = 2.98；95% CI 1.64 - 5.40）和经济担忧（OR = 2.33；95% CI 1.27 - 4.30）。心理社会危险因素包括精神质和神经质人格特质（分别为OR = 1.06；95% CI 1.02 - 1.10和OR = 1.07；95% CI 1.04 - 1.10）以及妊娠压力（OR = 1.04；95% CI 1.02 - 1.07）。
抑郁症状在妊娠晚期产前门诊就诊者中很常见。早期识别抑郁症的干预措施应针对有流产史和经济担忧的老年女性。干预策略可以是提供更多社会支持并促进积极应对策略。研究结果支持一项建议，即产前服务应考虑在常规产前护理中纳入抑郁症筛查。
