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腹膜透析中的阴茎和全身性钙化防御

Penile and generalised calciphylaxis in peritoneal dialysis.

作者信息

Sarkis Edmond

机构信息

Department of Internal Medicine, Cooper Medical Center, Camden, New Jersey, USA.

出版信息

BMJ Case Rep. 2015 Apr 16;2015:bcr2014209153. doi: 10.1136/bcr-2014-209153.

Abstract

This is a rare case of penile and generalised calciphylaxis. We describe the case of a patient admitted to our hospital for septic shock and necrotic skin findings, end-stage renal disease on peritoneal dialysis. Skin findings turned out to be calciphyactic lesions. The patient was taken to the operating room for penile debridement and started on antibiotics. He was treated with sodium thiosulfate and switched to haemodialysis. Calciphylaxis is a rare disease in which the treatment is basically supportive. Further studies are needed to identify the risk factors, mechanisms of disease and treatment modalities.

摘要

这是一例罕见的阴茎及全身性钙化防御病例。我们描述了一名因感染性休克和皮肤坏死表现入院的患者,该患者处于腹膜透析的终末期肾病阶段。皮肤表现最终证实为钙化防御性病变。患者被送往手术室进行阴茎清创术,并开始使用抗生素治疗。他接受了硫代硫酸钠治疗,随后转为血液透析。钙化防御是一种罕见疾病,其治疗基本上以支持治疗为主。需要进一步研究以确定危险因素、疾病机制和治疗方式。

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Penile and generalised calciphylaxis in peritoneal dialysis.腹膜透析中的阴茎和全身性钙化防御
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Revascularization surgery for penile calciphylaxis.阴茎钙化性血闭症的血运重建手术。
J Vasc Surg. 2013 Dec;58(6):1665-7. doi: 10.1016/j.jvs.2013.02.030. Epub 2013 Apr 6.
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Sodium thiosulfate therapy for calcific uremic arteriolopathy.硫代硫酸钠治疗钙化性尿毒症性小动脉病。
Clin J Am Soc Nephrol. 2013 Jul;8(7):1162-70. doi: 10.2215/CJN.09880912. Epub 2013 Mar 21.
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Calciphylaxis mimicking penile gangrene: a case report.模仿阴茎坏疽的钙过敏症:一例报告
ScientificWorldJournal. 2009 Dec 16;9:1355-9. doi: 10.1100/tsw.2009.150.
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Calciphylaxis from nonuremic causes: a systematic review.非尿毒症病因所致的钙过敏症:一项系统综述
Clin J Am Soc Nephrol. 2008 Jul;3(4):1139-43. doi: 10.2215/CJN.00530108. Epub 2008 Apr 16.

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