Gubskiĭ Iu I, Boldeskul A E, Primak R G, Zadorina O V
Ukr Biokhim Zh (1978). 1989 Jul-Aug;61(4):94-9.
Physiochemical conformity of the alpha-tocopherol interaction with hepatic microsomal membranes has been studied by means of fluorescent probes (pyrene and 1-anilinonaphthalene-8-sulphonate). The microsomal membrane microviscosity is shown to sharply decrease under conditions of the antioxidant deficiency with vitamin E expelled into animals normalizes microviscosity, but feebly influences the microsomal surface charge. Microcalorimetry has been used to establish that penetration of tocopherol into microsomal membranes was accompanied by the exothermic effect.
已通过荧光探针(芘和1-苯胺基萘-8-磺酸盐)研究了α-生育酚与肝微粒体膜相互作用的物理化学一致性。结果表明,在抗氧化剂缺乏的情况下,微粒体膜微粘度急剧下降,而将维生素E注入动物体内可使微粘度恢复正常,但对微粒体表面电荷的影响微弱。微量热法已用于确定生育酚渗透到微粒体膜中伴随着放热效应。