Suppr超能文献

加纳一家教学医院患者口服抗糖尿病药物的依从性

Adherence to oral anti-diabetic drugs among patients attending a Ghanaian teaching hospital.

作者信息

Bruce Suliasnaia P, Acheampong Franklin, Kretchy Irene

机构信息

Clinical Pharmacist, Pharmacy Department, Korle Bu Teaching Hospital. Accra ( Ghana ).

Principal Clinical Pharmacist, Emergency Department, Korle Bu Teaching Hospital. Accra ( Ghana ).

出版信息

Pharm Pract (Granada). 2015 Jan-Mar;13(1):533. doi: 10.18549/pharmpract.2015.01.533. Epub 2015 Mar 15.

Abstract

BACKGROUND

The burden of diabetes mellitus, especially Type-2, continues to increase across the world. Medication adherence is considered an integral component in its management. Poor glycemic controls due to medication nonadherence accelerates the development of long-term complications which consequently leads to increased hospitalization and mortality.

OBJECTIVE

This study examined the level of adherence to oral antidiabetic drugs among patients who visited the teaching hospital and explored the probable contributory factors to non-adherence.

METHODS

A cross-sectional descriptive study using systematic sampling to collect quantitative data was undertaken. Questionnaires were administered to outpatients of the medical department of a teaching hospital in Ghana. Logistic regression was performed with statistical significance determined at p<0.05.

RESULTS

A total of 200 diabetic patients participated in the study. Using the Morisky Medication Adherence scale, the level of adherence determined was 38.5%. There were significant correlations between level of adherence and educational level [(OR)=1.508; (CI 0.805-2.825), P=0.019), and mode of payment [(OR)=1.631; (CI 0.997-2.669), P=0.05).

CONCLUSION

Adherence in diabetic patients was low among respondents and this can be improved through education, counseling and reinforcement of self-care. There were several possible factors that contributed to the low adherence rate which could benefit from further studies.

摘要

背景

糖尿病负担,尤其是2型糖尿病负担在全球持续增加。药物依从性被认为是糖尿病管理的一个重要组成部分。因药物不依从导致的血糖控制不佳会加速长期并发症的发展,进而导致住院率和死亡率上升。

目的

本研究调查了到教学医院就诊的患者口服抗糖尿病药物的依从水平,并探讨了不依从的可能促成因素。

方法

采用系统抽样进行横断面描述性研究以收集定量数据。对加纳一家教学医院内科门诊患者进行问卷调查。采用逻辑回归分析,以p<0.05为具有统计学意义。

结果

共有200名糖尿病患者参与了本研究。使用莫氏药物依从性量表确定的依从水平为38.5%。依从水平与教育程度[(比值比)=1.508;(可信区间0.805 - 2.825),P = 0.019]以及支付方式[(比值比)=1.631;(可信区间0.997 - 2.669),P = 0.05]之间存在显著相关性。

结论

受访者中糖尿病患者的依从性较低,可通过教育、咨询和强化自我护理来改善。导致依从率低的因素有几个,值得进一步研究。

相似文献

1
Adherence to oral anti-diabetic drugs among patients attending a Ghanaian teaching hospital.
Pharm Pract (Granada). 2015 Jan-Mar;13(1):533. doi: 10.18549/pharmpract.2015.01.533. Epub 2015 Mar 15.
4
Adherence to Oral Hypoglycemic Drugs among Type 2 Diabetic Patients in a Resource-Poor Setting.
Int J Appl Basic Med Res. 2020 Apr-Jun;10(2):102-109. doi: 10.4103/ijabmr.IJABMR_270_19. Epub 2020 Apr 2.
7
Adherence to Antidiabetic Medications Among Sudanese Individuals With Type 2 Diabetes Mellitus: A Cross-Sectional Survey.
J Patient Exp. 2020 Apr;7(2):163-168. doi: 10.1177/2374373519831073. Epub 2019 Mar 13.
9
Association between patients' beliefs and oral antidiabetic medication adherence in a Chinese type 2 diabetic population.
Patient Prefer Adherence. 2016 Jun 27;10:1161-7. doi: 10.2147/PPA.S105600. eCollection 2016.
10
Evaluation of medication adherence among Lebanese diabetic patients.
Pharm Pract (Granada). 2018 Oct-Dec;16(4):1291. doi: 10.18549/PharmPract.2018.04.1291. Epub 2018 Dec 4.

引用本文的文献

1
Machine learning applications to classify and monitor medication adherence in patients with type 2 diabetes in Ethiopia.
Front Endocrinol (Lausanne). 2025 Mar 20;16:1486350. doi: 10.3389/fendo.2025.1486350. eCollection 2025.
2
Assessment of Medication Adherence in Diabetes Mellitus Patients at a Tertiary Care Teaching Hospital in India.
Cureus. 2025 Feb 2;17(2):e78391. doi: 10.7759/cureus.78391. eCollection 2025 Feb.
3
Factors Associated with Antidiabetic Medications and Dietary Recommendation Adherence Among Patients with Type 2 Diabetes.
Glob J Qual Saf Healthc. 2024 Jun 17;8(1):3-14. doi: 10.36401/JQSH-23-52. eCollection 2025 Feb.
4
Insulin therapy adherence and its associated factors among diabetic patients in a Ghanaian primary care hospital.
PLoS One. 2025 Jan 24;20(1):e0312094. doi: 10.1371/journal.pone.0312094. eCollection 2025.
6
8
Nexus between constructs of social cognitive theory model and diabetes self-management among Ghanaian diabetic patients: A mediation modelling approach.
PLOS Glob Public Health. 2022 Jul 25;2(7):e0000736. doi: 10.1371/journal.pgph.0000736. eCollection 2022.
10
Medication Adherence and Contributing Factors Among Type 2 Diabetes Patients at Adama Hospital Medical College in Eastern Ethiopia.
SAGE Open Nurs. 2023 Feb 20;9:23779608231158975. doi: 10.1177/23779608231158975. eCollection 2023 Jan-Dec.

本文引用的文献

1
Medication adherence among ambulatory patients with type 2 diabetes in a tertiary healthcare setting in southwestern Nigeria.
Pharm Pract (Granada). 2011 Apr;9(2):72-81. doi: 10.4321/s1886-36552011000200003. Epub 2011 Jun 17.
2
Measuring the rate of therapeutic adherence among outpatients with T2DM in Egypt.
Saudi Pharm J. 2010 Oct;18(4):225-32. doi: 10.1016/j.jsps.2010.07.004. Epub 2010 Jul 30.
3
Factors related to patient adherence to antidiabetic drug therapy.
Rev Lat Am Enfermagem. 2009 Jan-Feb;17(1):46-51. doi: 10.1590/s0104-11692009000100008.
5
A randomized trial of direct-to-patient communication to enhance adherence to beta-blocker therapy following myocardial infarction.
Arch Intern Med. 2008 Mar 10;168(5):477-83; discussion 483; quiz 447. doi: 10.1001/archinternmed.2007.132.
6
Economic costs of diabetes in the U.S. In 2007.
Diabetes Care. 2008 Mar;31(3):596-615. doi: 10.2337/dc08-9017.
7
Factors associated with adherence to drug therapy: a population-based study.
Eur J Clin Pharmacol. 2007 Mar;63(3):307-14. doi: 10.1007/s00228-006-0246-4. Epub 2007 Jan 9.
8
Medicines information and adherence in HIV/AIDS patients.
J Clin Pharm Ther. 2006 Feb;31(1):7-15. doi: 10.1111/j.1365-2710.2006.00696.x.
9
Global prevalence of diabetes: estimates for the year 2000 and projections for 2030.
Diabetes Care. 2004 May;27(5):1047-53. doi: 10.2337/diacare.27.5.1047.
10
Factors associated with therapy noncompliance in type-2 diabetes patients.
Salud Publica Mex. 2003 May-Jun;45(3):191-7. doi: 10.1590/s0036-36342003000300008.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验