Bruce Suliasnaia P, Acheampong Franklin, Kretchy Irene
Clinical Pharmacist, Pharmacy Department, Korle Bu Teaching Hospital. Accra ( Ghana ).
Principal Clinical Pharmacist, Emergency Department, Korle Bu Teaching Hospital. Accra ( Ghana ).
Pharm Pract (Granada). 2015 Jan-Mar;13(1):533. doi: 10.18549/pharmpract.2015.01.533. Epub 2015 Mar 15.
The burden of diabetes mellitus, especially Type-2, continues to increase across the world. Medication adherence is considered an integral component in its management. Poor glycemic controls due to medication nonadherence accelerates the development of long-term complications which consequently leads to increased hospitalization and mortality.
This study examined the level of adherence to oral antidiabetic drugs among patients who visited the teaching hospital and explored the probable contributory factors to non-adherence.
A cross-sectional descriptive study using systematic sampling to collect quantitative data was undertaken. Questionnaires were administered to outpatients of the medical department of a teaching hospital in Ghana. Logistic regression was performed with statistical significance determined at p<0.05.
A total of 200 diabetic patients participated in the study. Using the Morisky Medication Adherence scale, the level of adherence determined was 38.5%. There were significant correlations between level of adherence and educational level [(OR)=1.508; (CI 0.805-2.825), P=0.019), and mode of payment [(OR)=1.631; (CI 0.997-2.669), P=0.05).
Adherence in diabetic patients was low among respondents and this can be improved through education, counseling and reinforcement of self-care. There were several possible factors that contributed to the low adherence rate which could benefit from further studies.
糖尿病负担,尤其是2型糖尿病负担在全球持续增加。药物依从性被认为是糖尿病管理的一个重要组成部分。因药物不依从导致的血糖控制不佳会加速长期并发症的发展,进而导致住院率和死亡率上升。
本研究调查了到教学医院就诊的患者口服抗糖尿病药物的依从水平,并探讨了不依从的可能促成因素。
采用系统抽样进行横断面描述性研究以收集定量数据。对加纳一家教学医院内科门诊患者进行问卷调查。采用逻辑回归分析,以p<0.05为具有统计学意义。
共有200名糖尿病患者参与了本研究。使用莫氏药物依从性量表确定的依从水平为38.5%。依从水平与教育程度[(比值比)=1.508;(可信区间0.805 - 2.825),P = 0.019]以及支付方式[(比值比)=1.631;(可信区间0.997 - 2.669),P = 0.05]之间存在显著相关性。
受访者中糖尿病患者的依从性较低,可通过教育、咨询和强化自我护理来改善。导致依从率低的因素有几个,值得进一步研究。