Omotosho Tobiloba Oyejide Alex, Senghore Thomas
Department of Nursing and Reproductive Health, The University of the Gambia, Banjul, Gambia.
Department of Surgery, Edward Francis Small Teaching Hospital, Banjul, Gambia.
Diabetes Metab Syndr Obes. 2024 Jul 9;17:2683-2692. doi: 10.2147/DMSO.S464761. eCollection 2024.
Type 2 Diabetes Mellitus (DM) is a significant public health problem in The Gambia. While therapeutic non-adherence is widely recognized as a common and costly problem, very little is known about therapeutic adherence behavior among patients with diabetes in The Gambia.
The objective of this study was to determine the prevalence and factors that influence diabetic therapeutic non-adherence behavior among patients with type 2 diabetes in The Gambia.
A cross-sectional study design was used, and participants were recruited from Edward Francis Small Teaching Hospital (EFSTH) and Kanifing General Hospital (KGH). The sample size of 145 patients with type 2 diabetes was included and data was collected using a structured questionnaire. Adherence to anti-diabetic medications was measured using the Morisky Medications Adherence Scale (MMAS-8). Logistic regression was used to determine the factors associated with diabetic therapeutic non-adherence.
The prevalence of non-adherence to anti-diabetic treatment was 27.6%. Perceived barrier (forgetfulness, long-term medication use, and medication side effects) to diabetic treatment (OR = 0.265, 95% CI: 0.113-0.621, = 0.041) was statistically significantly associated with non-adherence to anti-diabetic treatment. However, the frequency of doctor's visits (OR = 0.310, 95% CI: 0.046-2.111) was not significantly associated with non-adherence to anti-diabetic treatment.
The rate of non-adherence to antidiabetic treatment in this study was high. Perceived barriers to antidiabetic treatment such as forgetfulness, long-term medication use, and medication side effects influenced therapeutic non-adherence to antidiabetic treatment. While interventions should focus on how to eliminate these barriers, health education on diabetic self-care may help reinforce the importance of medication adherence to prevent complications.
2型糖尿病（DM）是冈比亚一个重大的公共卫生问题。虽然治疗不依从被广泛认为是一个常见且代价高昂的问题，但对于冈比亚糖尿病患者的治疗依从行为却知之甚少。
本研究的目的是确定冈比亚2型糖尿病患者中糖尿病治疗不依从行为的患病率及影响因素。
采用横断面研究设计，参与者从爱德华·弗朗西斯·斯莫尔教学医院（EFSTH）和卡尼芬综合医院（KGH）招募。纳入了145例2型糖尿病患者的样本量，并使用结构化问卷收集数据。使用莫利斯基药物依从性量表（MMAS - 8）测量抗糖尿病药物的依从性。采用逻辑回归确定与糖尿病治疗不依从相关的因素。
抗糖尿病治疗不依从的患病率为27.6%。糖尿病治疗的感知障碍（健忘、长期用药和药物副作用）（OR = 0.265，95%CI：0.113 - 0.621，P = 0.041）与抗糖尿病治疗不依从在统计学上显著相关。然而，就诊频率（OR = 0.310，95%CI：0.046 - 2.111）与抗糖尿病治疗不依从无显著相关性。
本研究中抗糖尿病治疗的不依从率较高。糖尿病治疗的感知障碍，如健忘、长期用药和药物副作用，影响了抗糖尿病治疗的不依从。虽然干预措施应侧重于如何消除这些障碍，但糖尿病自我护理的健康教育可能有助于强化药物依从性对预防并发症的重要性。
