Bomela Nolunkcwe J
Department of Research Management, Nelson Mandela Metropolitan University, University Way, Summerstrand, Port Elizabeth, Eastern Cape, 6031, South Africa.
BMC Public Health. 2015 Mar 19;15:273. doi: 10.1186/s12889-015-1597-5.
Major changes in health policy, health service delivery, specific protocols, guidelines and recommendations for the management of common causes of maternal death have been developed in South Africa since the advent of the current democratic government. However, maternal mortality ratio remains high. The scientific community has conducted numerous studies on maternal mortality in South Africa; save for an analysis of the causes of maternal deaths, stratified by province. This study examines the geographic distribution of maternal causes of death in South Africa.
A pooled cross-sectional dataset for the years 2002-2006 retrieved from the vital registration database of Statistics South Africa was used to analyse maternal causes of death. About 8773 maternal deaths between 10-55 years were analysed using frequency tables, cross-tabulations and logistic regression. Maternal mortality ratios (MMR), odds ratios (OR) and 95% confidence intervals (CI) were used to analyse provincial disparities.
MMR was highest in the Free State (286/100,000) and lowest in the Western Cape (87/100,000). Tuberculosis (10.4%) was the leading single indirect cause of maternal deaths while hypertensive disorders (9.1%) were the leading direct cause of death. KwaZulu-Natal women had a significantly higher risk of dying from sepsis (aOR=3.1,95% CI=1.2-7.9). North West women had the lowest risk of dying from hypertensive disorders (aOR=0.4,95% CI=0.2-0.7). The risk of dying from complications of labour was lowest for Gauteng women (aOR=0.4,95% CI=0.1-0.9). The 30-34 years age group had a significantly high risk (aOR=2.5,95% CI=1.6-4.0) of dying from abortion while the 25-29 years age group had a significantly higher risk of dying from maternal infectious diseases (aOR=2.3,95% CI=1.3-3.9). The 40-44 years age group had a significantly higher risk of dying from haemorrhage (aOR=2.3,95% CI=1.3-3.9 and the 45+ age group from other maternal diseases (aOR=3.3,95% CI=1.2-8.5) and miscellaneous direct causes (aOR=4.1,95% CI=1.7-9.9) respectively.
The study shows great variations in the distribution and causes of maternal deaths by age and provincial level. Poorer provinces had lower MMR than the better off provinces. The provincial variations in the leading causes of death indicate the importance of targeted interventions at sub-national level.
自当前民主政府上台以来,南非在卫生政策、卫生服务提供、特定规程、指南以及孕产妇死亡常见病因管理建议等方面发生了重大变化。然而,孕产妇死亡率仍然很高。科学界对南非的孕产妇死亡率进行了大量研究;除了按省份分层分析孕产妇死亡原因外。本研究考察了南非孕产妇死亡原因的地理分布情况。
使用从南非统计局人口动态登记数据库中检索到的2002 - 2006年汇总横断面数据集来分析孕产妇死亡原因。对10至55岁之间约8773例孕产妇死亡病例使用频率表、交叉表和逻辑回归进行分析。孕产妇死亡率(MMR)、比值比(OR)和95%置信区间(CI)用于分析省级差异。
自由州的孕产妇死亡率最高(286/100,000),西开普省最低(87/100,000)。结核病(10.4%)是孕产妇死亡的首要单一间接原因,而高血压疾病(9.1%)是首要直接死因。夸祖鲁 - 纳塔尔省的妇女死于败血症的风险显著更高(调整后比值比[aOR]=3.1,95%置信区间[CI]=1.2 - 7.9)。西北省的妇女死于高血压疾病的风险最低(aOR=0.4,95% CI=0.2 - 0.7)。豪登省的妇女死于分娩并发症的风险最低(aOR=0.4,95% CI=0.1 - 0.9)。30 - 34岁年龄组死于堕胎的风险显著较高(aOR=2.5,95% CI=1.6 - 4.0),而25 - 29岁年龄组死于孕产妇传染病的风险显著更高(aOR=2.3,95% CI=1.3 - 3.9)。40 - 44岁年龄组死于出血的风险显著更高(aOR=2.3,95% CI=1.3 - 3.9),45岁及以上年龄组分别死于其他孕产妇疾病(aOR=3.3,95% CI=1.2 - 8.5)和其他直接原因(aOR=4.1,95% CI=1.7 - 9.9)的风险显著更高。
该研究表明,孕产妇死亡的分布和原因在年龄和省级层面存在很大差异。较贫困省份的孕产妇死亡率低于较富裕省份。主要死因的省级差异表明在国家以下层面进行有针对性干预的重要性。