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抑郁症亚型、抑郁严重程度与饮食质量之间的关联:BiDirect研究的横断面研究结果

Associations between depression subtypes, depression severity and diet quality: cross-sectional findings from the BiDirect Study.

作者信息

Rahe Corinna, Baune Bernhard T, Unrath Michael, Arolt Volker, Wellmann Jürgen, Wersching Heike, Berger Klaus

机构信息

Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany.

Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, SA, Australia.

出版信息

BMC Psychiatry. 2015 Mar 4;15:38. doi: 10.1186/s12888-015-0426-9.

Abstract

BACKGROUND

Depression is supposed to be associated with an unhealthy lifestyle including poor diet. The objective of this study was to investigate differences in diet quality between patients with a clinical diagnosis of depression and population-based controls. Additionally, we aimed to examine effects of specific depression characteristics on diet by analyzing if diet quality varies between patients with distinct depression subtypes, and if depression severity is associated with diet quality.

METHODS

The study included 1660 participants from the BiDirect Study (n = 840 patients with depression, n = 820 population-based controls). The psychiatric assessment was based on clinical interviews and a combination of depression scales in order to provide the classification of depression subtypes and severity. Diet quality scores, reflecting the adherence to a healthy dietary pattern, were calculated on the basis of an 18-item food frequency questionnaire. Using analysis of covariance, we calculated adjusted means of diet quality scores and tested differences between groups (adjusted for socio-demographic, lifestyle-, and health-related factors).

RESULTS

We found no differences in diet quality between controls and patients with depression if depression was considered as one entity. However, we did find differences between patients with distinct subtypes of depression. Patients with melancholic depression reported the highest diet quality scores, whereas patients with atypical depression reported the lowest scores. Depression severity was not associated with diet quality.

CONCLUSIONS

Previous literature has commonly treated depression as a homogeneous entity. However, subtypes of depression may be associated with diet quality in different ways. Further studies are needed to enlighten the diet-depression relationship and the role of distinct depression subtypes.

摘要

背景

抑郁症被认为与包括不良饮食在内的不健康生活方式有关。本研究的目的是调查临床诊断为抑郁症的患者与基于人群的对照组在饮食质量上的差异。此外,我们旨在通过分析不同抑郁症亚型患者的饮食质量是否不同,以及抑郁严重程度是否与饮食质量相关,来研究特定抑郁特征对饮食的影响。

方法

该研究纳入了来自双向研究的1660名参与者(n = 840名抑郁症患者,n = 820名基于人群的对照组)。精神科评估基于临床访谈和抑郁量表的组合,以提供抑郁症亚型和严重程度的分类。基于一份包含18个条目的食物频率问卷计算饮食质量得分,以反映对健康饮食模式的依从性。使用协方差分析,我们计算了饮食质量得分的调整均值,并检验了组间差异(对社会人口统计学、生活方式和健康相关因素进行了调整)。

结果

如果将抑郁症视为一个整体,我们发现对照组和抑郁症患者在饮食质量上没有差异。然而,我们确实发现不同抑郁症亚型患者之间存在差异。忧郁性抑郁症患者的饮食质量得分最高,而非典型抑郁症患者的得分最低。抑郁严重程度与饮食质量无关。

结论

以往文献通常将抑郁症视为一个同质的实体。然而,抑郁症的亚型可能以不同方式与饮食质量相关。需要进一步研究以阐明饮食与抑郁症的关系以及不同抑郁症亚型的作用。

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