• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

中国老年人健康生活方式与认知功能的关系:抑郁症状的中介作用。

The relationship between healthy lifestyles and cognitive function in Chinese older adults: the mediating effect of depressive symptoms.

机构信息

School of Management, Shandong Second Medical University, 261053, Weifang, Shandong, China.

出版信息

BMC Geriatr. 2024 Mar 28;24(1):299. doi: 10.1186/s12877-024-04922-5.

DOI:10.1186/s12877-024-04922-5
PMID:38549104
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10979595/
Abstract

BACKGROUND

Previous studies have proven the positive relationship between healthy lifestyles and cognitive function in older adults. However, the specific impacts and mechanisms require further investigation. Therefore, this study aimed to investigate whether healthy lifestyles and cognitive function were associated with Chinese older adults and whether depressive symptoms mediated their association.

METHODS

8272 valid samples were included using the latest data from the Chinese Longitudinal Healthy Longevity Survey (CLHLS). Pearson's test was applied to investigate the relationship between the key variables. Regression models were employed to examine the mediating effects of healthy lifestyles, using Sobel's test and the bootstrap method to confirm path effects.

RESULTS

There was a significant correlation between healthy lifestyles, depressive symptoms, and cognitive function (p < 0.01). Healthy lifestyles directly impact cognitive function (β = 0.162, p < 0.01). Healthy lifestyles had a significant effect on depressive symptoms (β=-0.301, p < 0.01), while depressive symptoms have a significant impact on cognitive function (β=-0.108, p < 0.01). Depressive symptoms partially mediated the effect of healthy lifestyles on cognitive function (β = 0.032, p < 0.01). The Sobel and bootstrap tests confirmed the robustness of the regression analysis results.

CONCLUSION

Depressive symptoms mediate the relationship between healthy lifestyles and cognitive function. Our findings suggest that prevention strategies for cognitive impairment in older adults should focus on healthy lifestyles and mental health.

摘要

背景

先前的研究已经证明了健康的生活方式与老年人认知功能之间的积极关系。然而,具体的影响和机制仍需进一步研究。因此,本研究旨在探讨健康的生活方式和认知功能是否与中国老年人有关,以及抑郁症状是否在其中起中介作用。

方法

本研究使用中国老年健康长寿纵向研究(CLHLS)的最新数据,纳入了 8272 个有效样本。采用 Pearson 检验来研究关键变量之间的关系。采用回归模型来检验健康生活方式的中介效应,使用 Sobel 检验和 bootstrap 方法来确认路径效应。

结果

健康的生活方式、抑郁症状和认知功能之间存在显著相关性(p<0.01)。健康的生活方式直接影响认知功能(β=0.162,p<0.01)。健康的生活方式对抑郁症状有显著影响(β=-0.301,p<0.01),而抑郁症状对认知功能有显著影响(β=-0.108,p<0.01)。抑郁症状部分中介了健康的生活方式对认知功能的影响(β=0.032,p<0.01)。Sobel 和 bootstrap 检验证实了回归分析结果的稳健性。

结论

抑郁症状在健康的生活方式和认知功能之间起中介作用。我们的研究结果表明,预防老年人认知障碍的策略应侧重于健康的生活方式和心理健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e91/10979595/7e8eebb1330e/12877_2024_4922_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e91/10979595/e3b281fe97fb/12877_2024_4922_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e91/10979595/7e8eebb1330e/12877_2024_4922_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e91/10979595/e3b281fe97fb/12877_2024_4922_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e91/10979595/7e8eebb1330e/12877_2024_4922_Fig2_HTML.jpg

相似文献

1
The relationship between healthy lifestyles and cognitive function in Chinese older adults: the mediating effect of depressive symptoms.中国老年人健康生活方式与认知功能的关系:抑郁症状的中介作用。
BMC Geriatr. 2024 Mar 28;24(1):299. doi: 10.1186/s12877-024-04922-5.
2
The mediating and moderating effect of health-promoting lifestyle on frailty and depressive symptoms for Chinese community-dwelling older adults: A cross-sectional study.促进健康的生活方式对中国社区居住的老年人衰弱和抑郁症状的中介和调节作用:一项横断面研究。
J Affect Disord. 2024 Sep 15;361:91-96. doi: 10.1016/j.jad.2024.06.011. Epub 2024 Jun 8.
3
The Effects of a Healthy Lifestyle on Depressive Symptoms in Older Chinese Adults: The Mediating Role of Psychological Resilience.健康生活方式对中国老年成年人抑郁症状的影响:心理韧性的中介作用
Cureus. 2024 Mar 30;16(3):e57258. doi: 10.7759/cureus.57258. eCollection 2024 Mar.
4
Inter-relationship between cognitive performance and depressive symptoms and their association with quality of life in older adults: A network analysis based on the 2017-2018 wave of Chinese Longitudinal Healthy Longevity Survey (CLHLS).老年人认知表现与抑郁症状之间的相互关系及其与生活质量的关联:基于 2017-2018 年中国健康长寿纵向研究(CLHLS)的网络分析。
J Affect Disord. 2023 Jan 1;320:621-627. doi: 10.1016/j.jad.2022.09.159. Epub 2022 Oct 5.
5
Association between disability and cognitive function in older Chinese people: a moderated mediation of social relationships and depressive symptoms.老年人残疾与认知功能的关系:社会关系和抑郁症状的中介调节作用。
Front Public Health. 2024 Apr 16;12:1354877. doi: 10.3389/fpubh.2024.1354877. eCollection 2024.
6
The dilution effect of healthy lifestyles on the risk of cognitive function attributed to socioeconomic status among Chinese older adults: A national wide prospective cohort study.健康生活方式对中国老年人认知功能与社会经济地位关联的稀释效应:一项全国范围的前瞻性队列研究。
J Glob Health. 2024 Feb 2;14:04010. doi: 10.7189/jogh-14-04010.
7
Longitudinal associations between social relationships and cognitive function among Chinese older adults: The mediating role of healthy lifestyles.中国老年人社会关系与认知功能之间的纵向关联:健康生活方式的中介作用。
Geriatr Nurs. 2023 Sep-Oct;53:102-108. doi: 10.1016/j.gerinurse.2023.06.016. Epub 2023 Jul 19.
8
Sensory impairment and cognitive function among older adults in China: The mediating roles of anxiety and depressive symptoms.中国老年人的感觉障碍和认知功能:焦虑和抑郁症状的中介作用。
Int J Geriatr Psychiatry. 2023 Jan;38(1):e5866. doi: 10.1002/gps.5866.
9
Frailty, cognitive impairment, and depressive symptoms in Chinese older adults: an eight-year multi-trajectory analysis.中国老年人的脆弱性、认知障碍和抑郁症状:八年多轨迹分析。
BMC Geriatr. 2023 Dec 12;23(1):843. doi: 10.1186/s12877-023-04554-1.
10
Longitudinal trajectories of physical functioning among Chinese older adults: the role of depressive symptoms, cognitive functioning and subjective memory.中国老年人身体功能的纵向轨迹:抑郁症状、认知功能和主观记忆的作用。
Age Ageing. 2021 Sep 11;50(5):1682-1691. doi: 10.1093/ageing/afab135.

引用本文的文献

1
The effect of cognitive function heterogeneity on depression risk in older adults: a stratified analysis based on functional status.认知功能异质性对老年人抑郁风险的影响:基于功能状态的分层分析
Front Public Health. 2025 Aug 18;13:1624599. doi: 10.3389/fpubh.2025.1624599. eCollection 2025.
2
Positive mental health literacy and job well-being among palliative care nurses: the mediating effect of job crafting.姑息护理护士的积极心理健康素养与工作幸福感:工作重塑的中介作用。
BMC Psychol. 2025 Aug 20;13(1):949. doi: 10.1186/s40359-025-03206-w.
3
An Exploratory Study of Factors Associated with Medication Adherence in Chinese Rheumatoid Arthritis Patients.

本文引用的文献

1
Effect of a multimodal training on the ability of medical students to administer the MMSE: a comparative study.多模式训练对医学生进行 MMSE 测试能力的影响:一项比较研究。
BMC Med Educ. 2024 Feb 12;24(1):133. doi: 10.1186/s12909-024-05044-7.
2
A screening method for mild cognitive impairment in elderly individuals combining bioimpedance and MMSE.一种结合生物阻抗和简易精神状态检查表的老年轻度认知障碍筛查方法。
Front Aging Neurosci. 2024 Jan 24;16:1307204. doi: 10.3389/fnagi.2024.1307204. eCollection 2024.
3
Sleep Quality and Cognitive Abilities in the Greek Cohort of Epirus Health Study.
中国类风湿关节炎患者药物依从性相关因素的探索性研究
J Inflamm Res. 2025 Apr 10;18:4947-4959. doi: 10.2147/JIR.S513474. eCollection 2025.
4
Osteoporosis risk and its association with all-cause and cause-specific mortality among the elderly: a 16-year nationwide cohort study.骨质疏松症风险及其与老年人全因死亡率和特定病因死亡率的关联:一项为期16年的全国性队列研究。
BMC Geriatr. 2025 Mar 26;25(1):199. doi: 10.1186/s12877-025-05843-7.
5
Associations of social isolation with memory and cognitive function in middle-aged and older Chinese adults.中国中老年人社交隔离与记忆及认知功能的关联
Aging Clin Exp Res. 2025 Mar 8;37(1):71. doi: 10.1007/s40520-025-02987-9.
6
Network relationship between cognitive function and quality of life in community-dwelling older adults: an observational study from Beijing.社区居住老年人认知功能与生活质量的网络关系:一项来自北京的观察性研究
Front Public Health. 2025 Feb 7;12:1516895. doi: 10.3389/fpubh.2024.1516895. eCollection 2024.
7
Association between stroke and fracture and the mediating role of depression: a cross-sectional study from NHANES 2017 to 2020.中风与骨折之间的关联及抑郁的中介作用:一项基于2017年至2020年美国国家健康与营养检查调查(NHANES)的横断面研究
Front Neurol. 2025 Feb 5;16:1533565. doi: 10.3389/fneur.2025.1533565. eCollection 2025.
8
Association of cardiovascular health with cognitive function and the mediating effect of depressive state.心血管健康与认知功能的关联及抑郁状态的中介作用
Front Aging Neurosci. 2024 Dec 18;16:1465310. doi: 10.3389/fnagi.2024.1465310. eCollection 2024.
伊庇鲁斯健康研究希腊队列中的睡眠质量与认知能力
Nat Sci Sleep. 2024 Jan 17;16:33-42. doi: 10.2147/NSS.S436519. eCollection 2024.
4
Number of Teeth and Denture Use Are Associated with Frailty among Chinese Older Adults: A Cohort Study Based on the CLHLS from 2008 to 2018.牙齿数量和义齿使用与中国老年人虚弱有关:基于 2008 年至 2018 年 CLHLS 的队列研究。
J Nutr Health Aging. 2023;27(11):972-979. doi: 10.1007/s12603-023-2014-x.
5
Association of depression trajectories and subsequent hypertension and cardiovascular disease: findings from the CHARLS cohort.抑郁轨迹与随后高血压和心血管疾病的关联:来自 CHARLS 队列的研究结果。
J Hypertens. 2024 Mar 1;42(3):432-440. doi: 10.1097/HJH.0000000000003609. Epub 2023 Nov 1.
6
Healthy lifestyle in late-life, longevity genes, and life expectancy among older adults: a 20-year, population-based, prospective cohort study.晚年健康生活方式、长寿基因与老年人预期寿命:一项基于人群的 20 年前瞻性队列研究。
Lancet Healthy Longev. 2023 Oct;4(10):e535-e543. doi: 10.1016/S2666-7568(23)00140-X.
7
Longitudinal relationships between depressive symptoms and cognitive function after stroke: A cross-lagged panel design.中风后抑郁症状与认知功能的纵向关系:交叉滞后组设计。
J Psychosom Res. 2023 Nov;174:111486. doi: 10.1016/j.jpsychores.2023.111486. Epub 2023 Sep 9.
8
Profiles of lifestyle health behaviors and cognitive decline in older adults.老年人生活方式健康行为与认知衰退特征。
Alzheimers Dement. 2024 Jan;20(1):472-482. doi: 10.1002/alz.13459. Epub 2023 Sep 7.
9
Combined influence of depressive symptoms and systemic inflammation on cardiovascular diseases in China.抑郁症状与全身炎症对中国心血管疾病的综合影响。
J Psychosom Res. 2023 Nov;174:111480. doi: 10.1016/j.jpsychores.2023.111480. Epub 2023 Sep 1.
10
Depressive Symptoms, the Impact on ART Continuation, and Factors Associated with Symptom Improvement Among a Cohort of People Living with HIV in British Columbia, Canada.加拿大不列颠哥伦比亚省艾滋病毒感染者队列中抑郁症状、对 ART 持续治疗的影响,以及与症状改善相关的因素。
AIDS Behav. 2024 Jan;28(1):43-58. doi: 10.1007/s10461-023-04156-3. Epub 2023 Aug 26.