Kozlova I A, Trubnikov V I
Zh Nevropatol Psikhiatr Im S S Korsakova. 1989;89(8):65-8.
In an analysis of 225 families of probands with different forms of the course of children's schizophrenia, a hypothesis on the degree of their genetical similarity (or dissimilarity) was tested. Malignant and slow progredient form of children schizophrenia showed major genetical similarity (correlation coefficient 1.0) with the recurrent schizophrenia occupying a separate position having no common genetical predisposition factors with nuclear forms of schizophrenia. Paroxysmal progredient schizophrenia displayed a distinct genetical relation to any other form (genetical correlation coefficient ranging in 0.5-0.7).
在一项对225个患有不同病程形式儿童精神分裂症的先证者家庭的分析中,对其遗传相似程度(或不相似程度)的假设进行了检验。儿童精神分裂症的恶性和缓慢进展型与复发型精神分裂症表现出主要的遗传相似性(相关系数为1.0),复发型精神分裂症占据一个单独的位置,与核心型精神分裂症没有共同的遗传易患因素。阵发性进展型精神分裂症与其他任何形式都表现出明显的遗传关系(遗传相关系数在0.5至0.7之间)。