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胆管癌脊髓髓内转移:一例报告

Intramedullary spinal cord metastasis of cholangiocarcinoma: a case report.

作者信息

Faugeras Laurence, Cantineau Gaetan, Daisne Jean-Francois, Gustin Thierry, D'hondt Lionel

机构信息

Department of Medical Oncology, Centre Hospitalier Universitaire Dinant-Godinne, 1 Rue Dr G. Therasse, 5530, Yvoir, Belgium.

Department of Radiology, Centre Hospitalier Universitaire DinantMont-Godinne, Yvoir, Belgium.

出版信息

BMC Res Notes. 2015 Feb 14;8:41. doi: 10.1186/s13104-015-0998-y.

DOI:10.1186/s13104-015-0998-y
PMID:25889352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4340695/
Abstract

BACKGROUND

Cholangiocarcinomas are rare tumors, and metastasis to the intramedullary spinal cord is also rare. To the best of our knowledge, this is the first case of simultaneous cholangiocarcinoma and intramedullary spinal cord metastasis to be described in the medical literature.

CASE PRESENTATION

A 62-year-old Caucasian male with a cholangiocarcinoma presented pain around his left shoulder without any other symptoms. The results by magnetic resonance imaging and F18 fluorodeoxyglucose positron emission tomography/computer tomography revealed an intramedullary metastasis at the C4 level, with spinal cord compression, and numerous secondary parenchymal brain metastases.

CONCLUSION

This patient was treated successfully with a combination of radiotherapy, corticosteroids, and chemotherapy. He experienced complete relief of the symptoms and showed improvements upon subsequent radiological evaluations.

摘要

背景

胆管癌是一种罕见的肿瘤,转移至脊髓髓内也很罕见。据我们所知,这是医学文献中首次描述的同时发生胆管癌和脊髓髓内转移的病例。

病例介绍

一名62岁的白种男性胆管癌患者出现左肩周围疼痛,无其他症状。磁共振成像和F18氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描结果显示,C4水平存在髓内转移,伴有脊髓压迫,以及大量脑实质继发性转移。

结论

该患者通过放疗、皮质类固醇和化疗联合治疗成功。他的症状完全缓解,随后的影像学评估显示有所改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30ef/4340695/afdb81c44ea3/13104_2015_998_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30ef/4340695/8d70adecb48a/13104_2015_998_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30ef/4340695/21202600fec4/13104_2015_998_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30ef/4340695/afdb81c44ea3/13104_2015_998_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30ef/4340695/8d70adecb48a/13104_2015_998_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30ef/4340695/21202600fec4/13104_2015_998_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30ef/4340695/afdb81c44ea3/13104_2015_998_Fig3_HTML.jpg

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本文引用的文献

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Intramedullary spinal cord metastases from breast cancer: detection with (18)F-FDG PET/CT.乳腺癌脊髓内转移:(18)F-FDG PET/CT检测
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Brain metastasis and leptomeningeal carcinomatosis in a patient with cholangiocarcinoma.一名胆管癌患者发生脑转移和软脑膜癌病。
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Radiotherapy for patients with symptomatic intramedullary spinal cord metastasis.有症状的脊髓内转移瘤患者的放射治疗。
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N Engl J Med. 2010 Apr 8;362(14):1273-81. doi: 10.1056/NEJMoa0908721.
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