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迈向循证急诊医学:曼彻斯特皇家医院的最佳临床证据。最佳临床证据2:在髂筋膜神经阻滞中,镁能延长布比卡因的镇痛效果吗?

Towards evidence-based emergency medicine: best BETs from the Manchester Royal Infirmary. BET 2: does magnesium prolong the analgaesic effect of bupivacaine in a fascia iliaca nerve block?

作者信息

Kilgour Peter, Oni Babajide, Ghanayem Hisham, Tabone Dianne

机构信息

Royal Preston Hospital, Lancashire, UK.

Central Manchester University Hospitals, UK.

出版信息

Emerg Med J. 2015 May;32(5):415-6. doi: 10.1136/emermed-2015-204758.2.

DOI:10.1136/emermed-2015-204758.2
PMID:25890943
Abstract

A shortcut review was carried out to establish whether routine use of magnesium as an adjunct to bupivacaine fascia iliaca nerve block in femoral neck fracture was effective in prolonging its analgaesic effect. Forty-four papers were found using the reported searches, of which one presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of this paper are tabulated. It is concluded that while magnesium has the potential to prolong the analgaesic effect of bupivacaine further studies are needed to clarify its exact role and safety profile.

摘要

进行了一项简短综述,以确定在股骨颈骨折中常规使用镁作为布比卡因髂筋膜神经阻滞的辅助药物是否能有效延长其镇痛效果。通过报告的检索找到了44篇论文,其中一篇提供了回答该临床问题的最佳证据。本文的作者、出版日期和国家、研究的患者群体、研究类型、相关结果、结果及研究不足均列于表格中。结论是,虽然镁有可能延长布比卡因的镇痛效果,但仍需要进一步研究以明确其确切作用和安全性。

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