Ueda Takeshi, Ishida Eri, Kojima Yusuke, Yoshikawa Satoshi, Yonemoto Hitoshi
Rakuwakai Marutamachi Hospital, Emergency and General Internal Medicine, Kyoto, Japan.
J Neuroimaging. 2015 Nov-Dec;25(6):927-30. doi: 10.1111/jon.12246. Epub 2015 Apr 19.
The early prediction of hypoxic encephalopathy after cardiac arrest is challenging. Measurement of the optic nerve sheath diameter (ONSD) by using sonography is a straightforward, noninvasive technique to detect an increased intracranial pressure, which can even be conducted at the bedside. However, it remains unknown whether or not sonographic ONSD measurement is valuable as a prognostic indicator of hypoxic encephalopathy.
Seventeen patients after cardiac arrest were retrospectively enrolled in this study. ONSD measurements 3 mm behind the papilla were recorded. A Glasgow Outcome Scale score of 4 or above was considered to indicate a favorable prognosis.
The mean ONSD associated with a favorable prognosis was 5.0 mm (4.4-6.1 mm). The ONSD associated with a poor prognosis was 6.1 mm (5.4-7.2 mm). ONSD less than or equal to 5.4 mm was an indicator of a favorable prognosis, with a sensitivity of 83%, specificity of 73%, positive likelihood ratio of 3.1, and negative likelihood ratio of .23.
Sonographic ONSD measurement is a simple, rapid technique to assess the neurological prognosis after cardiac arrest.
心脏骤停后缺氧性脑病的早期预测具有挑战性。使用超声测量视神经鞘直径(ONSD)是一种直接、无创的检测颅内压升高的技术,甚至可以在床边进行。然而,超声测量ONSD作为缺氧性脑病的预后指标是否有价值仍不清楚。
本研究回顾性纳入了17例心脏骤停后的患者。记录乳头后3毫米处的ONSD测量值。格拉斯哥预后评分4分及以上被认为预后良好。
预后良好的患者平均ONSD为5.0毫米(4.4 - 6.1毫米)。预后不良的患者ONSD为6.1毫米(5.4 - 7.2毫米)。ONSD小于或等于5.4毫米是预后良好的指标,敏感性为83%,特异性为73%,阳性似然比为3.1,阴性似然比为0.23。
超声测量ONSD是评估心脏骤停后神经预后的一种简单、快速的技术。