Sreenivasan Vidhyapriya, Bobier William R
School of Optometry, Indiana University, United States.
School of Optometry and Vision Science, University of Waterloo, Ontario, Canada.
Vision Res. 2015 Jun;111(Pt A):105-13. doi: 10.1016/j.visres.2015.04.001. Epub 2015 Apr 16.
This research tested the hypothesis that the successful treatment of convergence insufficiency (CI) with vision-training (VT) procedures, leads to an increased capacity of vergence adaptation (VAdapt) allowing a more rapid downward adjustment of the convergence accommodation cross-link. Nine subjects with CI were recruited from a clinical population, based upon reduced fusional vergence amplitudes, receded near point of convergence or symptomology. VAdapt and the resulting changes to convergence accommodation (CA) were measured at specific intervals over 15 min (pre-training). Separate clinical measures of the accommodative convergence cross link, horizontal fusion limits and near point of convergence were taken and a symptomology questionnaire completed. Subjects then participated in a VT program composed of 2.5h at home and 1h in-office weekly for 12-14 weeks. Clinical testing was done weekly. VAdapt and CA measures were retaken once clinical measures normalized for 2 weeks (mid-training) and then again when symptoms had cleared (post-training). VAdapt and CA responses as well as the clinical measures were taken on a control group showing normal clinical findings. Six subjects provided complete data sets. CI clinical findings reached normal levels between 4 and 7 weeks of training but symptoms, VAdapt, and CA output remained significantly different from the controls until 12-14 weeks. The hypothesis was retained. The reduced VAdapt and excessive CA found in CI were normalized through orthoptic treatment. This time course was underestimated by clinical findings but matched symptom amelioration.
通过视觉训练(VT)程序成功治疗集合不足(CI)会导致集合适应(VAdapt)能力增强,从而使集合调节交叉联系能更快速地向下调整。基于融合性集合幅度降低、集合近点后移或症状表现,从临床人群中招募了9名患有CI的受试者。在15分钟内(训练前)的特定时间间隔测量VAdapt以及由此产生的集合调节(CA)变化。分别对调节性集合交叉联系、水平融合极限和集合近点进行临床测量,并完成症状问卷。受试者随后参加了一个VT项目,该项目包括每周在家进行2.5小时、在办公室进行1小时,持续12 - 14周。每周进行临床测试。一旦临床测量在2周内恢复正常(训练中期),然后在症状消除后(训练后)再次测量VAdapt和CA指标。对一组临床检查结果正常的对照组进行VAdapt和CA反应以及临床测量。6名受试者提供了完整的数据集。CI的临床检查结果在训练4至7周时达到正常水平,但症状、VAdapt和CA输出在12 - 14周之前仍与对照组有显著差异。该假设得到保留。在CI中发现的VAdapt降低和CA过度通过视光学治疗得以正常化。这一病程被临床检查结果低估,但与症状改善情况相符。