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对781例因左前降支冠状动脉孤立性阻塞而接受经皮腔内冠状动脉成形术或冠状动脉旁路移植术的患者进行长期随访。

Late follow-up of 781 patients undergoing percutaneous transluminal coronary angioplasty or coronary artery bypass grafting for an isolated obstruction in the left anterior descending coronary artery.

作者信息

Kramer J R, Proudfit W L, Loop F D, Goormastic M, Zimmerman K, Simpfendorfer C, Horner G

机构信息

Department of Cardiology, Cleveland Clinic Foundation, OH 44195-5066.

出版信息

Am Heart J. 1989 Dec;118(6):1144-53. doi: 10.1016/0002-8703(89)90002-1.

DOI:10.1016/0002-8703(89)90002-1
PMID:2589153
Abstract

Seven hundred eighty-one patients with isolated left anterior descending coronary atherosclerosis treated with either coronary artery bypass grafting or percutaneous transluminal coronary angioplasty between January 1980 and December 1984 were studied to determine late survival and event-free survival. Follow-up was complete in 775 patients (99.4%). Actuarial survival at 5 years was 98% for surgical patients and 95% for angioplasty patients (p = 0.02). Five-year event-free survival (freedom from myocardial infarction, bypass grafting, angioplasty, and death) was 93% for surgical patients and 62% for angioplasty patients. This study suggests that the higher initial cost and complexity of bypass surgery may be justified by superior long-term results.

摘要

1980年1月至1984年12月期间,对781例接受冠状动脉旁路移植术或经皮腔内冠状动脉成形术治疗的孤立性左前降支冠状动脉粥样硬化患者进行了研究,以确定其远期生存率和无事件生存率。775例患者(99.4%)完成了随访。手术患者5年精算生存率为98%,血管成形术患者为95%(p = 0.02)。手术患者5年无事件生存率(无心肌梗死、旁路移植术、血管成形术和死亡)为93%,血管成形术患者为62%。这项研究表明,旁路手术较高的初始成本和复杂性可能因其优异的长期效果而合理。

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