Chen Chen-Ling, Chang Ken-Jie, Wu Pei-Ying, Chi Chun-Han, Chang Shin-Tsu, Cheng Yuan-Yang
Department of Physical Medicine and Rehabilitation, Taichung Veterans General Hospital, Taichung, Taiwan.
Department of Physical Medicine and Rehabilitation, Taichung Veterans General Hospital, Taichung, Taiwan; Center for Geriatrics and Gerontology, Taichung Veterans General Hospital, Taichung, Taiwan; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan.
J Stroke Cerebrovasc Dis. 2015 Jun;24(6):1317-23. doi: 10.1016/j.jstrokecerebrovasdis.2015.02.002. Epub 2015 Apr 16.
The goal of the study was to compare the effects of isokinetic and isotonic strengthening program on the changes of muscle strength, functional capacity, life quality, and inflammatory cytokines in hemiparetic patients within 6 months of stroke attack.
Thirty-one participants were randomly assigned into either isotonic training group or isokinetic training group. Both training programs were carried out 5 days a week for a total of 4 weeks. Outcome measures included the peak isometric torque of knees at 90° flexion, the peak torque of knees extension and flexion at angular velocities 60°/s and 120°/s, Short Form 36 (SF-36) Health Survey Questionnaire, Timed Up and Go test, and inflammatory cytokines including high sensitivity C-reactive protein, interleukin-6, and tumor necrosis factor-α.
Seven patients were not able to complete the training program and were excluded from our study. The results from the remaining 24 patients showed that there were more peak torque, and SF-36 items significantly improved in the isokinetic training group compared with the isotonic group. The Timed Up and Go test and interleukin-6 were improved in both groups, but tumor necrosis factor-α was improved in only the isokinetic group. There were no significant differences between the improvements of the 2 groups except the isokinetic flexion torque at 60°/s and 120°/s.
Early strengthening exercise is important for subacute stroke patients, and isokinetic program, if accessible, can bring more significant benefits for them.
本研究的目的是比较等速和等张强化训练方案对中风发作6个月内偏瘫患者肌肉力量、功能能力、生活质量和炎性细胞因子变化的影响。
31名参与者被随机分为等张训练组或等速训练组。两组训练方案均每周进行5天,共4周。观察指标包括膝关节90°屈曲时的等长峰值扭矩、角速度为60°/秒和120°/秒时膝关节伸展和屈曲的峰值扭矩、简明健康状况调查量表(SF-36)、计时起立行走测试,以及炎性细胞因子,包括高敏C反应蛋白、白细胞介素-6和肿瘤坏死因子-α。
7名患者未能完成训练方案,被排除在本研究之外。其余24名患者的结果显示,与等张训练组相比,等速训练组的峰值扭矩更大,SF-36各项指标有显著改善。两组的计时起立行走测试结果和白细胞介素-6水平均有所改善,但只有等速训练组的肿瘤坏死因子-α水平得到改善。除60°/秒和120°/秒时的等速屈曲扭矩外,两组改善情况无显著差异差异。
早期强化运动对亚急性中风患者很重要,若有条件,等速训练方案能给他们带来更显著的益处。