Broumand Behrooz
From the Iran University of Medical Sciences, Tehran; Pars General Hospital, Tehran; and Iranian Society of Organ Transplantation, Tehran, Iran.
Exp Clin Transplant. 2015 Apr;13 Suppl 1:4-8.
In 2014, there is unanimous agreement that kidney transplant is the optimal treatment for most patients who have end-stage renal failure. Increasing organ shortage is the main obstacle that delays transplant and might even cause death while the patient is on the waiting list for kidney transplant. Many innovations have been proposed to increase the number of organs for transplant in different countries such as increasing awareness about organ donation, based on different cultures and religions. Support of religious and faith leaders exists for procurement of organs for transplant from patients with brain death or circulatory death. In the past decade, use of marginal and expandedcriteria deceased-donor transplant has been very helpful to expand the kidney donor pool. Dual kidney transplant is another procedure that may minimize the waiting list. The 1977 transport of kidneys from Minneapolis to Tehran helped change the life of a 15-year-old girl. At that time, we had the potential to change a life across 2 continents, even though our techniques were new. This should have provided the impetus to develop such a program. Presently, with progress in science, techniques, and organ shipment, it is our responsibility to reach across the globe to change the lives of many more young and adult patients waiting for kidney transplant. There are many countries in which kidneys from patients with brain or cardiac death are being discarded because of the unavailability of a transplant program in these countries, or because these countries have young transplant programs and very limited resources. If a global registry could be organized under the observation of the International Society of Nephrology and The Transplantation Society Sister Transplant Center Program, transplant teams would be able to use kidneys from patients with brain or cardiac death, with strict regulation of organ donation in accordance with World Health Organization guidelines.
2014年,人们一致认为肾移植是大多数终末期肾衰竭患者的最佳治疗方法。器官短缺日益严重,这是延迟移植的主要障碍,甚至可能导致患者在等待肾移植名单上时死亡。不同国家提出了许多创新措施来增加可移植器官的数量,比如基于不同文化和宗教提高对器官捐赠的认识。宗教和信仰领袖支持从脑死亡或循环死亡患者身上获取器官用于移植。在过去十年中,使用边缘供体和扩大标准的 deceased-donor 移植对扩大肾供体库非常有帮助。双肾移植是另一种可能减少等待名单的手术。1977年从明尼阿波利斯向德黑兰运送肾脏帮助改变了一名15岁女孩的生活。那时,尽管我们的技术还很新,但我们有能力改变两大洲人们的生活。这本应成为推动开展这样一个项目的动力。目前,随着科学、技术和器官运输方面的进步,我们有责任跨越全球,改变更多等待肾移植的年轻和成年患者的生活。有许多国家,由于这些国家没有移植项目,或者因为这些国家的移植项目起步较晚且资源非常有限,脑死亡或心脏死亡患者的肾脏正被丢弃。如果能在国际肾脏病学会和移植学会姐妹移植中心项目的监督下组织一个全球登记处,移植团队将能够使用脑死亡或心脏死亡患者的肾脏,同时根据世界卫生组织的指导方针严格规范器官捐赠。