Taydas Eren, Malik Mohammad U, Dhingra Abhinav, Russell Stuart, Chacko Matthews, Cameron Andrew M, Alqahtani Saleh, Gurakar Ahmet
From the Department of Internal Medicine, MedStar Franklin Square Medical Center, Baltimore, USA.
Exp Clin Transplant. 2015 Apr;13 Suppl 1:30-2.
Coronary artery disease may affect cirrhotic patients regardless of age and etiology of the underlying liver disease. Early identification of coronary artery disease is important to be able to achieve the best posttransplant outcomes and survival. The coronary artery calcium score can be used as a screening tool to supplement the results of cardiac stress tests to identify a subgroup of patients who may benefit from further investigation with coronary arteriogram. Arteriogram is an invasive test and may cause renal compromise and risk of bleeding associated with coagulopathy. The present retrospective study showed that coronary artery calcium score > 250 Agatston units may help select the subgroup of patients who will benefit from further investigation with cardiac catheterization, and determining this score may limit the risks of catheterization.
冠状动脉疾病可能影响肝硬化患者，无论其年龄及潜在肝脏疾病的病因如何。早期识别冠状动脉疾病对于实现最佳的移植后结局和生存率至关重要。冠状动脉钙化积分可作为一种筛查工具，以补充心脏负荷试验的结果，从而识别出可能从冠状动脉造影进一步检查中获益的患者亚组。冠状动脉造影是一种侵入性检查，可能导致肾功能损害以及与凝血病相关的出血风险。本回顾性研究表明，冠状动脉钙化积分>250阿加斯顿单位可能有助于选择将从心脏导管插入术进一步检查中获益的患者亚组，并且确定该积分可能会限制导管插入术的风险。
