Robson S C, Hunter S, Boys R J, Dunlop W
Department of Obstetrics, University of Newcastle Upon Tyne, England.
Am J Obstet Gynecol. 1989 Nov;161(5):1273-8. doi: 10.1016/0002-9378(89)90682-0.
Serial hemodynamic investigations were performed in 10 women with twin pregnancies at 20, 24, 28, 32, and 36 weeks' gestation and at 6 months after delivery. Cardiac output was measured by Doppler and cross-sectional echocardiography at the aortic, pulmonary, and mitral valves. Cardiac chamber size and ventricular function were investigated by M-mode echocardiography. The hemodynamic results were compared with those of 13 women with singleton pregnancies. Mean Doppler cardiac output was increased at 20 weeks of twin pregnancy (7.63 L/min) and showed no significant change during the remainder of pregnancy, but fell to 5.07 L/min after delivery. This increase was significantly greater than that recorded during singleton pregnancy, because of a relatively greater increase in heart rate. Twin pregnancy was associated with a significantly greater increase in left atrial dimension, but the increases in left ventricular dimensions, wall thickness, and function were comparable to those recorded in singleton pregnancy.
对10例双胎妊娠女性在妊娠20、24、28、32和36周时以及产后6个月进行了系列血流动力学研究。通过多普勒和横断面超声心动图测量主动脉瓣、肺动脉瓣和二尖瓣处的心输出量。通过M型超声心动图研究心脏腔室大小和心室功能。将血流动力学结果与13例单胎妊娠女性的结果进行比较。双胎妊娠20周时平均多普勒心输出量增加（7.63升/分钟），在妊娠其余时间无显著变化，但产后降至5.07升/分钟。由于心率相对增加幅度更大，这种增加显著大于单胎妊娠期间记录的增加幅度。双胎妊娠与左心房内径显著更大的增加相关，但左心室内径、壁厚和功能的增加与单胎妊娠记录的情况相当。
