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经皮内镜下胃造口术(PEG)不会加重儿童呕吐。

Percutaneous endoscopic gastrostomy (PEG) does not worsen vomiting in children.

作者信息

Kakade Madhavi, Coyle David, McDowell Dermot T, Gillick John

机构信息

Department of Pediatric Surgery, Temple Street Children's University Hospital, Dublin 1, Ireland,

出版信息

Pediatr Surg Int. 2015 Jun;31(6):557-62. doi: 10.1007/s00383-015-3707-y. Epub 2015 Apr 17.

Abstract

PURPOSE

We aimed to evaluate the rate and examine potential predictors of subsequent anti-reflux procedures in a population undergoing percutaneous endoscopic gastrostomy (PEG) insertion.

MATERIALS

We retrospectively reviewed the pre- and post-operative clinical course of patients undergoing PEG insertion over a 10-year period with respect to indication, underlying co-morbidity, and GER investigation and management.

RESULTS

We reviewed data on 170 patients. Neurological disability (e.g., cerebral palsy) was the most common underlying condition in those undergoing PEG insertion (n = 104) followed by cystic fibrosis (n = 29). Oropharyngeal dysphagia and failure to thrive were the commonest indications for PEG. Eight patients (4.7%) reported increased frequency of vomiting after PEG, 6 (75%) of whom had a pre-operative diagnosis of GER. Two (25%) patients from this sub-group subsequently required anti-reflux surgery. Patient's with neurological disease were not at increased risk of new-onset GER or increased vomiting following PEG insertion compared to those with non-neurological conditions (p = 0.259). In total, 8 (4.7%) and 7 (4.1%) patients underwent fundoplication and gastrojejunal tube insertion, respectively.

CONCLUSIONS

PEG insertion does not appear to induce symptomatic gastro-oesophageal reflux in the majority of children, suggesting that in the majority of cases, a concurrent anti-reflux procedure is unnecessary. Parents should be counseled accordingly.

摘要

目的

我们旨在评估接受经皮内镜下胃造口术(PEG)置入的人群中后续抗反流手术的发生率,并检查其潜在预测因素。

材料

我们回顾性分析了10年间接受PEG置入患者的术前和术后临床病程,内容包括适应证、基础合并症以及胃食管反流(GER)的检查和处理情况。

结果

我们回顾了170例患者的数据。神经功能障碍(如脑瘫)是接受PEG置入患者中最常见的基础疾病(n = 104),其次是囊性纤维化(n = 29)。口咽吞咽困难和发育不良是PEG最常见的适应证。8例患者(4.7%)报告PEG术后呕吐频率增加,其中6例(75%)术前诊断为GER。该亚组中有2例(25%)患者随后需要进行抗反流手术。与非神经疾病患者相比,神经疾病患者在PEG置入后新发GER或呕吐增加的风险并未增加(p = 0.259)。总共有8例(4.7%)和7例(4.1%)患者分别接受了胃底折叠术和胃空肠造瘘管置入术。

结论

PEG置入在大多数儿童中似乎不会诱发有症状的胃食管反流,这表明在大多数情况下,同时进行抗反流手术是不必要的。应据此向家长提供咨询。

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