Kakade Madhavi, Coyle David, McDowell Dermot T, Gillick John
Department of Pediatric Surgery, Temple Street Children's University Hospital, Dublin 1, Ireland,
Pediatr Surg Int. 2015 Jun;31(6):557-62. doi: 10.1007/s00383-015-3707-y. Epub 2015 Apr 17.
We aimed to evaluate the rate and examine potential predictors of subsequent anti-reflux procedures in a population undergoing percutaneous endoscopic gastrostomy (PEG) insertion.
We retrospectively reviewed the pre- and post-operative clinical course of patients undergoing PEG insertion over a 10-year period with respect to indication, underlying co-morbidity, and GER investigation and management.
We reviewed data on 170 patients. Neurological disability (e.g., cerebral palsy) was the most common underlying condition in those undergoing PEG insertion (n = 104) followed by cystic fibrosis (n = 29). Oropharyngeal dysphagia and failure to thrive were the commonest indications for PEG. Eight patients (4.7%) reported increased frequency of vomiting after PEG, 6 (75%) of whom had a pre-operative diagnosis of GER. Two (25%) patients from this sub-group subsequently required anti-reflux surgery. Patient's with neurological disease were not at increased risk of new-onset GER or increased vomiting following PEG insertion compared to those with non-neurological conditions (p = 0.259). In total, 8 (4.7%) and 7 (4.1%) patients underwent fundoplication and gastrojejunal tube insertion, respectively.
PEG insertion does not appear to induce symptomatic gastro-oesophageal reflux in the majority of children, suggesting that in the majority of cases, a concurrent anti-reflux procedure is unnecessary. Parents should be counseled accordingly.
我们旨在评估接受经皮内镜下胃造口术(PEG)置入的人群中后续抗反流手术的发生率,并检查其潜在预测因素。
我们回顾性分析了10年间接受PEG置入患者的术前和术后临床病程,内容包括适应证、基础合并症以及胃食管反流(GER)的检查和处理情况。
我们回顾了170例患者的数据。神经功能障碍(如脑瘫)是接受PEG置入患者中最常见的基础疾病(n = 104),其次是囊性纤维化(n = 29)。口咽吞咽困难和发育不良是PEG最常见的适应证。8例患者(4.7%)报告PEG术后呕吐频率增加,其中6例(75%)术前诊断为GER。该亚组中有2例(25%)患者随后需要进行抗反流手术。与非神经疾病患者相比,神经疾病患者在PEG置入后新发GER或呕吐增加的风险并未增加(p = 0.259)。总共有8例(4.7%)和7例(4.1%)患者分别接受了胃底折叠术和胃空肠造瘘管置入术。
PEG置入在大多数儿童中似乎不会诱发有症状的胃食管反流,这表明在大多数情况下,同时进行抗反流手术是不必要的。应据此向家长提供咨询。