Xu Xinbo, Li Wenming, Jin Tong, Qian Ye, Wei Dongmin, Sun Ruijie, Liu Dayu, Lei Dapeng, Pan Xinliang
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2014 Dec;28(24):1934-7.
To analyze the clinical characters, surgical treatments and prognosis of differentiated thyroid carcinoma (DTC) with laryngeal or tracheal invasion.
Forty-six cases including 33 papillary and 13 follicular were retrospectively reviewed. Thirty-four cases with tracheal invasion received conservative resection (17), window resection (11) and sleeve resection (6). One case with subglottic invasion was performed subglottic partial laryngectomy. Eleven cases with trachea-laryngeal invasion received total laryngectomy(4), 3 shave technique and 4 preservative laryngectomy.
Complications included infections and hypocalcaemia, 15 patients got permanent fistula. 5-year survival rate in cases of tracheal shave resection was 88.2%, while 63.6% in those of window resection and 83.3% in those of sleeve resection. Survival rate within 5 years of patients received preservative laryngectomy was 62. 5%. Conclusion: With meticulous preoperative examination and positive surgical treatment, both survival rate and quality of life could be improved in patients of DTC with laryngeal or tracheal invasion.
分析侵犯喉或气管的分化型甲状腺癌（DTC）的临床特征、手术治疗方法及预后。
回顾性分析46例患者，其中乳头状癌33例，滤泡状癌13例。34例侵犯气管的患者接受了保守切除术（17例）、开窗切除术（11例）和袖状切除术（6例）。1例声门下侵犯患者接受了声门下部分喉切除术。11例气管-喉侵犯患者接受了全喉切除术（4例）、3例削除术和4例保留喉切除术。
并发症包括感染和低钙血症，15例患者出现永久性瘘管。气管削除切除术患者的5年生存率为88.2%，开窗切除术患者为63.6%，袖状切除术患者为83.3%。接受保留喉切除术患者的5年生存率为62.5%。结论：通过细致的术前检查和积极的手术治疗，侵犯喉或气管的DTC患者的生存率和生活质量均可得到提高。
