Halawa Eman F, Draz Iman, Ahmed Dalia, Shaheen Hala A
Faculty of Medicine, Cairo University, Cairo, Egypt
Faculty of Medicine, Cairo University, Cairo, Egypt.
J Child Neurol. 2015 Nov;30(13):1736-42. doi: 10.1177/0883073815579706. Epub 2015 Apr 20.
Convulsive status epilepticus is a common neurologic emergency in pediatrics. We aimed to study the etiology, clinical features, and prognostic factors among pediatric patients with convulsive status epilepticus. Seventy patients were included in this cohort study from pediatric emergency department of the specialized Children Hospital of Cairo University. The outcome was evaluated using the Glasgow Outcome Score. Acute symptomatic etiology was the most common cause of convulsive status epilepticus. Refractory convulsive status epilepticus was observed more significantly in cases caused by acute symptomatic etiologies. The outcome was mortality in 26 (37.1%) patients, severe disability in 15 (21.4%), moderate disability in 17 (24.3%), and good recovery in 12 (17.1%) patients. The significant predictor of mortality was lower modified Glasgow Coma Scale score on admission, whereas lower modified Glasgow Coma Scale score on admission and refractory convulsive status epilepticus were the significant predictors for disability and mortality.
惊厥性癫痫持续状态是儿科常见的神经系统急症。我们旨在研究惊厥性癫痫持续状态患儿的病因、临床特征及预后因素。本队列研究纳入了开罗大学儿童医院儿科急诊科的70例患者。采用格拉斯哥预后评分评估预后。急性症状性病因是惊厥性癫痫持续状态最常见的原因。在急性症状性病因导致的病例中，难治性惊厥性癫痫持续状态更为显著。结果显示，26例（37.1%）患者死亡，15例（21.4%）严重残疾，17例（24.3%）中度残疾，12例（17.1%）患者恢复良好。死亡的显著预测因素是入院时改良格拉斯哥昏迷量表评分较低，而入院时改良格拉斯哥昏迷量表评分较低和难治性惊厥性癫痫持续状态是残疾和死亡的显著预测因素。
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