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慢性四肢瘫痪患者的主观睡眠障碍与生活质量

Subjective sleep disturbances and quality of life in chronic tetraplegia.

作者信息

Spong J, Graco M, Brown D J, Schembri R, Berlowitz D J

机构信息

Institute for Breathing and Sleep, Bowen Centre, Austin Hospital, Heidelberg, Victoria, Australia.

Spinal Research Institute, Melbourne, Australia.

出版信息

Spinal Cord. 2015 Aug;53(8):636-40. doi: 10.1038/sc.2015.68. Epub 2015 Apr 21.

DOI:10.1038/sc.2015.68
PMID:25896348
Abstract

STUDY DESIGN

This is a cross-sectional survey.

OBJECTIVES

The objective of this study was to evaluate the subjective sleep disturbances and quality of life in chronic tetraplegia.

SETTING

This study was conducted in a community sample from Victoria, Australia.

METHODS

People with tetraplegia were mailed a survey battery including the following: demographic questions; Karolinska Sleepiness Scale (KSS); Basic Nordic Sleepiness Questionnaire; Functional Outcomes of Sleep Questionnaire (FOSQ); Multivariate Apnoea Prediction Index and Assessment of Quality of Life (AQoL) Questionnaire. Scores were compared with the best available normative data.

RESULTS

A total of 163 of 424 (38%) surveys were returned (77% male; 39% sensory and motor complete; mean age±s.d.=46±14 years; mean years since injury=11±8 years). The AQoL health utility score (0.31±0.29) was significantly lower than published population norms. FOSQ total (17.55±2.57) and KSS (3.93±2.27) scores were no different from the best available population data. People with tetraplegia reported worse sleep habits, symptoms and quality than a normal population, as indicated on 17 of 21 questions on the Basic Nordic Sleep Questionnaire. Multivariate analysis found that greater injury severity (coefficient (95% CI)=0.14 (0.10, 0.18)), increasing age (-0.004 (-0.008, -0.001)) and worse sleep symptoms (-0.005 (-0.009, -0.0003)) were all significantly associated with reduced quality of life.

CONCLUSION

People with chronic tetraplegia experience more subjective sleep problems and worse quality of life than their able-bodied counterparts. Quality of life is related to injury severity, age and sleep symptoms. Treating the sleep disorders experienced by people living with tetraplegia has the potential to improve their health and well-being.

摘要

研究设计

这是一项横断面调查。

目的

本研究的目的是评估慢性四肢瘫痪患者的主观睡眠障碍和生活质量。

背景

本研究在澳大利亚维多利亚州的一个社区样本中进行。

方法

向四肢瘫痪患者邮寄一套调查问卷,包括以下内容:人口统计学问题;卡罗林斯卡嗜睡量表(KSS);北欧基本嗜睡问卷;睡眠功能结果问卷(FOSQ);多变量呼吸暂停预测指数和生活质量评估问卷(AQoL)。将得分与现有的最佳标准数据进行比较。

结果

424份调查问卷共收回163份(38%)(男性占77%;感觉和运动完全性损伤占39%;平均年龄±标准差=46±14岁;受伤平均年限=11±8年)。AQoL健康效用得分(0.31±0.29)显著低于已公布的人群标准。FOSQ总分(17.55±2.57)和KSS得分(3.93±2.27)与现有的最佳人群数据无差异。北欧基本睡眠问卷21个问题中的17个显示,四肢瘫痪患者报告的睡眠习惯、症状和质量比正常人群更差。多变量分析发现,损伤严重程度越高(系数(95%置信区间)=0.14(0.10,0.18))、年龄增长(-0.004(-0.008,-0.001))和睡眠症状越差(-0.005(-0.009,-0.0003))均与生活质量下降显著相关。

结论

与身体健全的人相比,慢性四肢瘫痪患者经历更多的主观睡眠问题,生活质量更差。生活质量与损伤严重程度、年龄和睡眠症状有关。治疗四肢瘫痪患者的睡眠障碍有可能改善他们的健康和幸福感。

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