Bantsar A, Hilgers G, Pszona S, Rabus H, Szeflinski Z
National Center for Nuclear Research (NCBJ), ul. Andrzeja Soltana 7, Otwock-Swierk 05-400, Poland
Physikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, Braunschweig D-38116, Germany.
Radiat Prot Dosimetry. 2015 Sep;166(1-4):253-6. doi: 10.1093/rpd/ncv191. Epub 2015 Apr 20.
In view of the upcoming radiation therapy with carbon ions, the ionisation structure of the carbon ion track at the nanometre scale is of particular interest. Two different nanodosimeters capable of measuring track structure of ionising particles in a gas target equivalent to a nanometric site in condensed matter were involved in the presented experimental investigation, namely the NCBJ Jet Counter and the PTB Ion Counter. At the accelerator facility of the HIL in Warsaw, simulated nanometric volumes were irradiated with carbon ions of 45 and 76 MeV of kinetic energy, corresponding to a range in the tissue of ∼85 µm and ∼190 µm, respectively. The filling gas of both nanodosimeters' ionisation volume was molecular nitrogen N2, and the ionisation cluster size distributions, i.e. the statistical distribution of the number of ionizations produced by one single primary carbon ion in the filling gas, were measured for the two primary particle energies.
鉴于即将进行的碳离子放射治疗，纳米尺度下碳离子径迹的电离结构尤为令人关注。本实验研究中使用了两种不同的纳米剂量仪，它们能够测量与凝聚态物质中的纳米位点等效的气体靶中电离粒子的径迹结构，即NCBJ喷流计数器和PTB离子计数器。在华沙HIL的加速器设施中，用动能为45 MeV和76 MeV的碳离子对模拟纳米体积进行辐照，这两种能量的碳离子在组织中的射程分别约为85 µm和190 µm。两种纳米剂量仪电离体积的填充气体均为分子氮N₂，并针对两种初级粒子能量测量了电离簇尺寸分布，即单个初级碳离子在填充气体中产生的电离数的统计分布。
