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创伤性脑损伤后前五年社区融合轨迹的建模

Modeling of Community Integration Trajectories in the First Five Years after Traumatic Brain Injury.

作者信息

Andelic Nada, Arango-Lasprilla Juan Carlos, Perrin Paul B, Sigurdardottir Solrun, Lu Juan, Landa Laiene Olabarrieta, Forslund Marit V, Roe Cecilie

机构信息

1 Department of Physical Medicine and Rehabilitation, Oslo University Hospital Ulleval , Oslo, Norway .

2 Institute of Health and Society, Research Centre for Habilitation and Rehabilitation Models and Services, Faculty of Medicine, University of Oslo , Oslo, Norway .

出版信息

J Neurotrauma. 2016 Jan 1;33(1):95-100. doi: 10.1089/neu.2014.3844. Epub 2015 Jun 11.

Abstract

The aims of this study were to assess the trajectories of community integration in individuals with traumatic brain injury (TBI) through one, two, and five years post-injury and to examine whether those trajectories could be predicted by demographic and injury characteristics. A longitudinal cohort study was conducted with 105 individuals with moderate-to-severe TBI admitted to a trauma referral center in 2005-2007. Demographics and injury-related factors were extracted from medical records. At the one-, two- and five-year follow-ups, community integration was measured by the Community Integration Questionnaire (CIQ). A hierarchical linear model (HLM) examined whether longitudinal trajectories of community integration could be predicted by: time, sex, age, relationship status, education, employment status, occupation, acute Glasgow Coma Scale score, cause of injury, days in post-traumatic amnesia (PTA), computed tomography Marshall Score, and Injury Severity Score. CIQ scores improved across the three time-points (p<0.001). Additionally, higher trajectories of community integration were predicted by being single at the time of injury (p<.001), higher level of education (p=0.006), employment (p<0.001), and a shorter length of PTA (p<0.001). In a follow-up HLM with interaction terms, time*PTA was statistically significant (p<0.001), suggesting that participants with longer PTA increased in community integration more rapidly than those with shorter PTA. The longitudinal course of community integration described in this study may help rehabilitation professionals to plan more extensive follow-ups and targeted rehabilitation programs in the early stage of recovery for patients with specific demographic and injury characteristics.

摘要

本研究的目的是评估创伤性脑损伤(TBI)患者伤后1年、2年和5年的社区融入轨迹,并检验这些轨迹是否可由人口统计学和损伤特征预测。对2005年至2007年入住创伤转诊中心的105例中重度TBI患者进行了一项纵向队列研究。从医疗记录中提取人口统计学和损伤相关因素。在1年、2年和5年随访时,采用社区融入问卷(CIQ)测量社区融入情况。采用分层线性模型(HLM)检验社区融入的纵向轨迹是否可由以下因素预测:时间、性别、年龄、恋爱状况、教育程度、就业状况、职业、急性格拉斯哥昏迷量表评分、损伤原因、创伤后遗忘(PTA)天数、计算机断层扫描马歇尔评分和损伤严重程度评分。CIQ评分在三个时间点均有所改善(p<0.001)。此外,伤时单身(p<0.001)、教育程度较高(p=0.006)、就业(p<0.001)和PTA时间较短(p<0.001)可预测更高的社区融入轨迹。在一项包含交互项的随访HLM中,时间*PTA具有统计学意义(p<0.001),表明PTA时间较长的参与者比PTA时间较短的参与者社区融入增加得更快。本研究中描述的社区融入纵向过程可能有助于康复专业人员为具有特定人口统计学和损伤特征的患者在恢复早期制定更广泛的随访计划和有针对性的康复方案。

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