零容忍：内吞作用中的两亲性螺旋。

Zero tolerance: amphipathic helices in endocytosis.

机构信息

Mechanochemical Cell Biology Building, Division of Biomedical Cell Biology, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK.

出版信息

Dev Cell. 2015 Apr 20;33(2):119-20. doi: 10.1016/j.devcel.2015.04.007.

DOI:10.1016/j.devcel.2015.04.007

PMID:25898162

Abstract

Endocytosis is the physical battle to form a new vesicle in the face of counteracting forces, such as membrane tension. Skruzny et al. (2015) and Miller et al. (2015) now shed light on endocytic proteins that bear a "Helix 0" and on the proteins' role in the struggle to make clathrin-coated vesicles.

摘要

内吞作用是在面对诸如膜张力等拮抗力量时形成新囊泡的物理斗争。Skruzny 等人（2015 年）和 Miller 等人（2015 年）现在揭示了带有“螺旋 0”的内吞作用蛋白，以及这些蛋白在形成网格蛋白包被囊泡的斗争中的作用。