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MET Mutation Associated with Responsiveness to Crizotinib.

作者信息

Waqar Saiama N, Morgensztern Daniel, Sehn Jennifer

机构信息

Division of Medical Oncology, Department of Internal Medicine, Washington University, School of Medicine, St. Louis, MO.

Division of Medical Oncology, Department of Internal Medicine, Washington University, School of Medicine, St. Louis, MO.

出版信息

J Thorac Oncol. 2015 May;10(5):e29-e31. doi: 10.1097/JTO.0000000000000478.

DOI:10.1097/JTO.0000000000000478
PMID:25898962
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4408879/
Abstract
摘要

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本文引用的文献

1
Diagnostic utility of targeted next-generation sequencing in problematic cases.靶向下一代测序在疑难病例中的诊断效用。
Am J Surg Pathol. 2014 Apr;38(4):534-41. doi: 10.1097/PAS.0000000000000161.
2
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal.利用 cBioPortal 进行复杂癌症基因组学和临床特征的综合分析
Sci Signal. 2013 Apr 2;6(269):pl1. doi: 10.1126/scisignal.2004088.
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Gastric cancer cell line Hs746T harbors a splice site mutation of c-Met causing juxtamembrane domain deletion.胃癌细胞系 Hs746T 存在 c-Met 剪接位点突变，导致跨膜结构域缺失。
Biochem Biophys Res Commun. 2010 Apr 16;394(4):1042-6. doi: 10.1016/j.bbrc.2010.03.120. Epub 2010 Mar 21.
4
Ethnic differences and functional analysis of MET mutations in lung cancer.肺癌中 MET 突变的种族差异和功能分析。
Clin Cancer Res. 2009 Sep 15;15(18):5714-23. doi: 10.1158/1078-0432.CCR-09-0070. Epub 2009 Sep 1.
5
Somatic mutations lead to an oncogenic deletion of met in lung cancer.体细胞突变导致肺癌中met基因的致癌性缺失。
Cancer Res. 2006 Jan 1;66(1):283-9. doi: 10.1158/0008-5472.CAN-05-2749.