Canales-Johnson Andrés, Silva Carolina, Huepe David, Rivera-Rei Álvaro, Noreika Valdas, Garcia María del Carmen, Silva Walter, Ciraolo Carlos, Vaucheret Esteban, Sedeño Lucas, Couto Blas, Kargieman Lucila, Baglivo Fabricio, Sigman Mariano, Chennu Srivas, Ibáñez Agustín, Rodríguez Eugenio, Bekinschtein Tristan A
Medical Research Council Cognition and Brain Sciences Unit, Cambridge, UK Department of Psychology, University of Cambridge, Cambridge, UK Laboratory of Cognitive and Social Neuroscience, Universidad Diego Portales, Santiago, Buenos Aires, Chile.
Laboratory of Cognitive and Social Neuroscience, Universidad Diego Portales, Santiago, Buenos Aires, Chile.
Cereb Cortex. 2015 Nov;25(11):4490-503. doi: 10.1093/cercor/bhv076. Epub 2015 Apr 21.
Interoception, the perception of our body internal signals, plays a key role in maintaining homeostasis and guiding our behavior. Sometimes, we become aware of our body signals and use them in planning and strategic thinking. Here, we show behavioral and neural dissociations between learning to follow one's own heartbeat and metacognitive awareness of one's performance, in a heartbeat-tapping task performed before and after auditory feedback. The electroencephalography amplitude of the heartbeat-evoked potential in interoceptive learners, that is, participants whose accuracy of tapping to their heartbeat improved after auditory feedback, was higher compared with non-learners. However, an increase in gamma phase synchrony (30-45 Hz) after the heartbeat auditory feedback was present only in those participants showing agreement between objective interoceptive performance and metacognitive awareness. Source localization in a group of participants and direct cortical recordings in a single patient identified a network hub for interoceptive learning in the insular cortex. In summary, interoceptive learning may be mediated by the right insular response to the heartbeat, whereas metacognitive awareness of learning may be mediated by widespread cortical synchronization patterns.
内感受，即对我们身体内部信号的感知，在维持体内平衡和指导我们的行为方面起着关键作用。有时，我们会意识到自己的身体信号，并在规划和战略思考中运用它们。在此，我们展示了在有听觉反馈前后进行的心跳敲击任务中，学习跟随自己的心跳与对自身表现的元认知意识之间的行为和神经分离。与未学习者相比，内感受学习者（即在听觉反馈后敲击心跳的准确性提高的参与者）的心跳诱发电位的脑电图幅度更高。然而，心跳听觉反馈后伽马相位同步（30 - 45赫兹）的增加仅出现在那些客观内感受表现与元认知意识一致的参与者中。一组参与者的源定位和一名患者的直接皮层记录确定了岛叶皮层中内感受学习的一个网络枢纽。总之，内感受学习可能由右侧岛叶对心跳的反应介导，而学习的元认知意识可能由广泛的皮层同步模式介导。
