Chen Chun-Ti, Gubbels Marc-Jan
Department of Biology, Boston College, Chestnut Hill, MA 02467, USA.
Department of Biology, Boston College, Chestnut Hill, MA 02467, USA.
Trends Parasitol. 2015 Jun;31(6):229-30. doi: 10.1016/j.pt.2015.04.003. Epub 2015 Apr 19.
The centrosome serves as a central hub coordinating multiple cellular events in eukaryotes. A recent study in Toxoplasma gondii revealed a unique bipartite structure of the centrosome, which coordinates the nuclear cycle (S-phase and mitosis) and budding cycle (cytokinesis) of the parasite, and deciphers the principle behind flexible apicomplexan cell division modes.
中心体作为一个核心枢纽,协调真核生物中的多种细胞活动。最近一项关于弓形虫的研究揭示了中心体独特的二分结构,该结构协调寄生虫的核周期(S期和有丝分裂)和出芽周期(胞质分裂),并解读了顶复门寄生虫灵活的细胞分裂模式背后的原理。