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外科定制聚丙烯网片作为无针单切口吊带与经闭孔尿道中段吊带术治疗女性压力性尿失禁的比较研究

Surgeon-tailored polypropylene mesh as a needleless single-incision sling versus TVT-O for the treatment of female stress urinary incontinence: a comparative study.

作者信息

ElSheemy Mohammed S, Fathy Hesham, Hussein Hussein A, Hussein Eman A, Hassan Sarah Mohamed

机构信息

Urology Department, Kasr Al-Ainy Hospital, Cairo University, Cairo, Egypt,

出版信息

Int Urol Nephrol. 2015 Jun;47(6):937-44. doi: 10.1007/s11255-015-0974-4. Epub 2015 Apr 22.

Abstract

PURPOSE

To compare safety and efficacy of surgeon-tailored polypropylene mesh through needleless single-incision technique (STM) versus tension-free vaginal tape-obturator (TVT-O) aiming to decrease cost of treatment of stress urinary incontinence (SUI). This is important in developing countries due to limited healthcare resources.

PATIENTS AND METHODS

A retrospective cohort study was done at Urology and Gynecology Departments (dual-center), Cairo University, from January 2011 to August 2013. STM was inserted in 72 females, while TVT-O was inserted in 48 females. Females evaluated by cough stress test, stress and urge incontinence quality of life questionnaire (SUIQQ), Q max and abdominal leak point pressure (ALPP) were included. Different factors were compared between both groups using paired t, Wilcoxon's signed rank, McNemar, Chi-square, Fisher's exact, independent t or Mann-Whitney tests.

RESULTS

Age, parity, previous surgeries, ALPP, intrinsic sphincter deficiency (ISD), associated prolapse and associated prolapse repair were comparable in both groups. No significant difference was found between both groups in postoperative complications (except groin pain), cure, SUIQQ indices improvement and Q max decline. In total, 65 (90 %) cured, 6 (8 %) improved while failure was detected in one (1 %) patient in STM group, while 42 (87 %) cured, 4 (8 %) improved and failure was detected in two (4 %) patients in TVT-O group. Presence of ISD (p = 0.565), urgency (p = 0.496), UUI (p = 0.531), previous surgeries (p = 0.345), associated urogenital prolapse (p = 0.218) or associated prolapse repair (p = 0.592) did not lead to any significant difference in outcome between both groups. Cost of mesh decreased from US$500 (TVT-O) to US$10 (STM).

CONCLUSION

Outcome of STM is comparable to TVT-O. Furthermore, STM is more economic.

摘要

目的

比较经无针单切口技术(STM)植入的外科定制聚丙烯网片与无张力阴道吊带闭孔术(TVT - O)治疗压力性尿失禁(SUI)的安全性和有效性,旨在降低治疗成本。鉴于医疗资源有限,这在发展中国家具有重要意义。

患者与方法

2011年1月至2013年8月在开罗大学泌尿外科和妇科(双中心)进行了一项回顾性队列研究。72名女性接受了STM植入,48名女性接受了TVT - O植入。纳入通过咳嗽压力试验、压力性和急迫性尿失禁生活质量问卷(SUIQQ)、最大尿流率(Q max)和腹压漏尿点压力(ALPP)评估的女性。使用配对t检验、Wilcoxon符号秩检验、McNemar检验、卡方检验、Fisher精确检验、独立t检验或Mann - Whitney检验比较两组之间的不同因素。

结果

两组在年龄、产次、既往手术史、ALPP、固有括约肌缺陷(ISD)、合并脱垂及合并脱垂修复情况方面具有可比性。两组在术后并发症(腹股沟疼痛除外)、治愈率、SUIQQ指数改善情况和Q max下降方面无显著差异。STM组共有65例(90%)治愈,6例(8%)改善,1例(1%)失败;TVT - O组有42例(87%)治愈,4例(8%)改善,2例(4%)失败。ISD的存在(p = 0.565)、急迫性(p = 0.496)、混合性尿失禁(UUI)(p = 0.531)、既往手术史(p = 0.345)、合并泌尿生殖系统脱垂(p = 0.218)或合并脱垂修复(p = 0.592)在两组结局中均未导致任何显著差异。网片成本从500美元(TVT - O)降至10美元(STM)。

结论

STM的治疗效果与TVT - O相当。此外,STM更经济。

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