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[冠状动脉闭塞时大鼠心脏的毛细血管系统]

[The capillary system of the rat heart in occlusion of the coronary artery].

作者信息

Sisakian S A, Matevosian R Sh

出版信息

Arkh Anat Gistol Embriol. 1989 Aug;97(8):15-8.

PMID:2589994
Abstract

In 74 white rats by means of non-injection++ method morphofunctional state of the myocardial capillary bed has been studied in dynamics at occlusion of descending branch of the left coronary artery. During the first week after the operation blood supply of the areas, adjoining the necrosis, increases at the expense of dilatation and some increase in number of functioning capillaries, that results in enlargement of the exchanging surface and capacity of the capillary bed. Beginning from the 12th day, the value of all these parameters decreases, however, they do not reach their initial level. By the end of the experiment (45 days) the number of the functioning capillaries somewhat decreases, but the capillary diameters remain increased. By that time in the myocardial areas, adjoining the necrosis a parviansiform capillary network without a definite orientation, concerning muscle fibers, has been formed.

摘要

通过非注射++法,对74只白鼠在左冠状动脉降支闭塞时心肌毛细血管床的形态功能状态进行了动态研究。术后第一周,邻近坏死区的供血通过功能毛细血管的扩张和数量的增加得以增加,这导致交换表面和毛细血管床容量增大。从第12天开始,所有这些参数的值下降,然而,它们并未降至初始水平。到实验结束时(45天),功能毛细血管数量有所减少,但毛细血管直径仍保持增大。此时,在邻近坏死区的心肌区域,已形成了一个与肌纤维无明确取向的细小毛细血管网络。

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