一名患有阻塞性睡眠呼吸暂停综合征的严重肥胖男子出现蛋白尿、肾小球肿大和局灶性肾小球硬化。
Proteinuria, glomerulomegaly and focal glomerulosclerosis in a grossly obese man with obstructive sleep apnea syndrome.
作者信息
Bailey R R, Lynn K L, Burry A F, Drennan C
机构信息
Department of Nephrology, Christchurch Hospital, New Zealand.
出版信息
Aust N Z J Med. 1989 Oct;19(5):473-4. doi: 10.1111/j.1445-5994.1989.tb00310.x.
Abstract
A grossly obese (149 kg) man with the sleep apnea syndrome was found to have proteinuria and a supernormal glomerular filtration rate. Renal histology showed glomerulomegaly and focal glomerulosclerosis. It is suggested that obesity may induce glomerular hyperfiltration and in turn glomerulosclerosis.
摘要
一名患有睡眠呼吸暂停综合征的严重肥胖男子（体重149千克）被发现有蛋白尿和超常的肾小球滤过率。肾脏组织学检查显示肾小球肿大和局灶性肾小球硬化。提示肥胖可能诱发肾小球高滤过，进而导致肾小球硬化。
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