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一名34岁原发性甲状旁腺功能亢进女性的骨硬化症。

Osteosclerosis in a thirty-four-year-old woman with primary hyperparathyroidism.

作者信息

Anbiaee Nadjme, Tafakhori Zahra, Moghadam-Ahmadi Amir, Akbarian Golsa

机构信息

Department of Oral and Maxillofacial Radiology, School of Dentistry and Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Department of Oral and Maxillofacial Radiology, School of Dentistry and Dental Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

出版信息

Iran J Radiol. 2015 Apr 22;12(2):e8260. doi: 10.5812/iranjradiol.8260. eCollection 2015 Apr.

DOI:10.5812/iranjradiol.8260
PMID:25901265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4393636/
Abstract

Hyperparathyroidism is an endocrine abnormality that frequently causes diffuse osteopenia in the bones. Osteosclerosis is a rare phenomenon in adults with primary hyperparathyroidism since the usual skeletal manifestation is generalized osteopenia. We describe a patient with generalized osteosclerosis in the jaws and skull in association with primary hyperparathyroidism, while the other skeletal bones had normal or decreased density.

摘要

甲状旁腺功能亢进是一种内分泌异常，常导致骨骼弥漫性骨质减少。骨硬化在原发性甲状旁腺功能亢进的成人中是一种罕见现象，因为常见的骨骼表现是全身性骨质减少。我们描述了一名原发性甲状旁腺功能亢进患者，其颌骨和颅骨出现全身性骨硬化，而其他骨骼的密度正常或降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c222/4393636/ecf10c90d4bf/Iranjradiol-12-02-8260-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c222/4393636/11bfeef28001/Iranjradiol-12-02-8260-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c222/4393636/0eb65ee91635/Iranjradiol-12-02-8260-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c222/4393636/fcd811c532bc/Iranjradiol-12-02-8260-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c222/4393636/ecf10c90d4bf/Iranjradiol-12-02-8260-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c222/4393636/11bfeef28001/Iranjradiol-12-02-8260-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c222/4393636/0eb65ee91635/Iranjradiol-12-02-8260-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c222/4393636/fcd811c532bc/Iranjradiol-12-02-8260-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c222/4393636/ecf10c90d4bf/Iranjradiol-12-02-8260-g004.jpg

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本文引用的文献

1
Primary hyperparathyroidism with multiple osteosclerotic lesions of the calvarium.原发性甲状旁腺功能亢进伴颅骨多发性骨硬化性病变。
J Bone Miner Res. 2003 Mar;18(3):410-2. doi: 10.1359/jbmr.2003.18.3.410.
2
Parathyroidectomy for primary hyperparathyroidism induces positive uncoupling and increases bone mineral density in cancellous bones.甲状旁腺切除术治疗原发性甲状旁腺功能亢进可诱导正向解偶联并增加松质骨的骨矿物质密度。
Clin Endocrinol (Oxf). 2000 Feb;52(2):203-9. doi: 10.1046/j.1365-2265.2000.00900.x.
3
Generalized osteosclerosis in primary hyperparathyroidism.
原发性甲状旁腺功能亢进症中的全身性骨硬化
Trans Am Clin Climatol Assoc. 1974;85:185-201.
4
Osteosclerosis in primary hyperparathyroidism.原发性甲状旁腺功能亢进症中的骨硬化
Am J Med. 1975 Jul;59(1):104-13. doi: 10.1016/0002-9343(75)90327-7.