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巧克力与健康相关生活质量:一项前瞻性研究。

Chocolate and health-related quality of life: a prospective study.

作者信息

Balboa-Castillo Teresa, López-García Esther, León-Muñoz Luz M, Pérez-Tasigchana Raúl F, Banegas José Ramón, Rodríguez-Artalejo Fernando, Guallar-Castillón Pilar

机构信息

Department of Public Health, School of Medicine, Universidad de la Frontera, Temuco, Chile.

Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid/IdiPaz, CIBERESP, Madrid, Spain.

出版信息

PLoS One. 2015 Apr 22;10(4):e0123161. doi: 10.1371/journal.pone.0123161. eCollection 2015.

Abstract

BACKGROUND

Chocolate consumption has been associated with a short-term reduction in blood pressure and cholesterol, and improvement of insulin sensitivity; however, participants could not be aware of presenting hypertension or hypercholesterolemia. Moreover, the effect of chocolate on mental health is uncertain. This study assessed the association of regular chocolate consumption with the physical (PCS) and mental (MCS) components of health-related quality of life (HRQL).

MATERIALS AND METHODS

We analyzed data from a cohort of 4599 individuals recruited in 2008-2010 and followed-up once prospectively to January 2013 (follow-up mean: 3.5 years). Regular chocolate consumption was assessed at baseline with a validated diet history. HRQL was assessed with the SF-12 v.2 at baseline and at follow-up. Analyses were performed with linear regression and adjusted for the main confounders, including HRQL at baseline.

RESULTS

At baseline, 72% of the study participants did not consume chocolate, 11% consumed ≤10 g/day and 17% >10 g/day. Chocolate consumption at baseline did not show an association with PCS and MCS of the SF-12 measured three years later. Compared to those who did not consume chocolate, the PCS scores were similar in those who consumed ≤10 g/day (beta: -0.07; 95% confidence interval (95% CI): -0.94 to 0.80) and in those who consumed >10 g/day (beta: 0.02; 95% CI:-0.71 to 0.75); corresponding figures for the MCS were 0.29; 95% CI: -0.67 to 1.26, and -0.57; 95%CI: -1.37 to 0.23. Similar results were found for sex, regardless of obesity, hypertension, hypercholesterolemia, diabetes or depression.

CONCLUSIONS

No evidence was found of an association between chocolate intake and the physical or mental components of HRQL.

摘要

背景

食用巧克力与短期内血压和胆固醇降低以及胰岛素敏感性改善有关;然而,参与者可能并未意识到自己患有高血压或高胆固醇血症。此外,巧克力对心理健康的影响尚不确定。本研究评估了经常食用巧克力与健康相关生活质量(HRQL)的身体(PCS)和心理(MCS)成分之间的关联。

材料与方法

我们分析了2008年至2010年招募的4599名个体队列的数据,并对其进行了一次前瞻性随访,直至2013年1月(随访平均时间:3.5年)。在基线时通过有效的饮食史评估巧克力的常规摄入量。在基线和随访时使用SF-12 v.2评估HRQL。采用线性回归进行分析,并对主要混杂因素进行调整,包括基线时的HRQL。

结果

在基线时,72%的研究参与者不食用巧克力,11%的参与者每天食用量≤10克,17%的参与者每天食用量>10克。基线时的巧克力摄入量与三年后测量的SF-12的PCS和MCS均无关联。与不食用巧克力的人相比,每天食用量≤10克的人(β:-0.07;95%置信区间(95%CI):-0.94至0.80)和每天食用量>10克的人(β:0.02;95%CI:-0.71至0.75)的PCS得分相似;MCS的相应数字分别为0.29;95%CI:-0.67至1.26,以及-0.57;95%CI:-1.37至0.23。无论性别、肥胖、高血压、高胆固醇血症、糖尿病或抑郁症如何,均得到类似结果。

结论

未发现巧克力摄入量与HRQL的身体或心理成分之间存在关联。

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