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泪囊鼻腔造口术造口肉芽肿:分类、治疗指征、管理方式及结果

The Dacryocystorhinostomy Ostium Granulomas: Classification, Indications for Treatment, Management Modalities and Outcomes.

作者信息

Ali Mohammad Javed, Wormald Peter John, Psaltis Alkis James

机构信息

Dacryology Service, L. V. Prasad Eye Institute , Hyderabad , India and.

出版信息

Orbit. 2015 Jun;34(3):146-51. doi: 10.3109/01676830.2015.1014510. Epub 2015 Apr 22.

Abstract

AIM

Ostium granulomas following dacryocystorhinostomy (DCR) have not been studied in detail previously. This study aims to classify the DCR-related granulomas based on their ostial locations and to assess the outcomes of their management.

METHODS

A retrospective consecutive case series of 47 ostial granulomas evaluated over a period of 2 years were included in this study. All patients underwent detailed endoscopic examination to assess the granuloma locations and their response to initial topical steroids treatment. Persistent granulomas either underwent further management with excision or intralesional steroids based on their location. Patients were followed up for a minimum of 6 months. The primary outcome measure was resolution of granuloma.

RESULTS

The mean age at presentation was 45 years with a female preponderance (68%). 70% (33/47) of granulomas were following external DCR and 30% (14/47) occurred in the setting of endonasal DCR. The most common location was an edge granuloma in 46.8% (22/47) followed by a combined granuloma in 21.2% (10/47). 91.4% (43/47) underwent initial treatment with topical nasal steroids. The remaining 4 (8.5%) underwent primary excision. Among those treated with topical steroids (n = 43), 9.3% (4/43) underwent further treatment with intralesional triamcinolone. Overall, 4.2% (2/47) recurred in 6 weeks following resolution and were treated with excision.

CONCLUSION

We recommend routine endoscopic evaluation of all the DCR ostia. Detection of granulomas in early stages and appropriate management as per guidelines proposed may aid in better outcomes.

摘要

目的

泪囊鼻腔吻合术(DCR)后造口肉芽肿此前尚未得到详细研究。本研究旨在根据造口位置对DCR相关肉芽肿进行分类,并评估其治疗效果。

方法

本研究纳入了连续2年评估的47例造口肉芽肿的回顾性病例系列。所有患者均接受详细的内镜检查,以评估肉芽肿的位置及其对初始局部类固醇治疗的反应。持续性肉芽肿根据其位置进一步接受切除或病灶内注射类固醇治疗。对患者进行至少6个月的随访。主要观察指标为肉芽肿的消退情况。

结果

患者就诊时的平均年龄为45岁,女性占多数(68%)。70%(33/47)的肉芽肿发生于外路DCR后,30%(14/47)发生于鼻内DCR。最常见的位置是边缘肉芽肿,占46.8%(22/47),其次是混合性肉芽肿,占21.2%(10/47)。91.4%(43/47)的患者最初接受局部鼻用类固醇治疗。其余4例(8.5%)接受了初次切除。在接受局部类固醇治疗的患者中(n = 43),9.3%(4/43)接受了病灶内注射曲安奈德的进一步治疗。总体而言,4.2%(2/47)在消退后6周复发,并接受了切除治疗。

结论

我们建议对所有DCR造口进行常规内镜评估。早期发现肉芽肿并按照建议的指南进行适当治疗可能有助于获得更好的治疗效果。

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