Scheen A J
Rev Med Liege. 2015 Jan;70(1):49-53.
Some patients are exposed to complex clinical situations, which impose a careful analysis of both the indications and contraindications of ongoing pharmacological treatments as well as of the dosing or drug adjustments to be proposed. This article illustrates some problems encountered when a new drug therapy is initiated, when medications with narrow therapeutic window should be supervised and when some drugs should be stopped mainly for safety reasons. The clinical case relates the story of a patient with type 2 diabetes, arterial hypertension and coronary heart disease, who presents a congestive heart failure associated with an episode of atrial fibrillation and a severe renal insufficiency.
一些患者面临复杂的临床情况，这需要对正在进行的药物治疗的适应证和禁忌证以及拟议的剂量或药物调整进行仔细分析。本文阐述了开始新的药物治疗、应监测治疗窗窄的药物以及主要出于安全原因应停用某些药物时所遇到的一些问题。该临床病例讲述了一名患有2型糖尿病、动脉高血压和冠心病的患者的故事，该患者出现了与房颤发作和严重肾功能不全相关的充血性心力衰竭。
