Greenspan Michael, Chehl Navdeep, Shawron Krista, Barnes Lisa, Li Hong, Avery Elizabeth, Sims Shannon, Losurdo John, Mobarhan Sohrab, Melson Joshua
Department of Medicine, Division of Digestive Diseases, Rush University Medical Center, 1725 West Harrison, Suite 206, Chicago, IL, 60612, USA.
Department of Neurological Sciences and Behavioral Sciences, Rush University Medical Center, 600 S. Paulina Street, Suite 1022g, Chicago, IL, 60612, USA.
Dig Dis Sci. 2015 Oct;60(10):2930-6. doi: 10.1007/s10620-015-3664-2. Epub 2015 Apr 23.
A significant proportion of the eligible population is non-adherent to colonoscopy for colorectal cancer (CRC) screening.
To define the demographic and clinical variables associated with non-adherence and multiple cancellations to scheduled colonoscopy within 1 year in a CRC screening and adenomatous polyp surveillance population.
This was an observational cohort study of 617 consecutive patients scheduled to undergo colonoscopy at an outpatient academic tertiary care center for CRC screening or adenomatous polyp surveillance from January 2012 to September 2012.
Overall, 551 patients (89.3%) were adherent and 66 (10.7%) were non-adherent to scheduled colonoscopy at 1 year. The relative risk for non-adherence was 5.42 [95% confidence interval (CI) 2.74-10.75] in patients undergoing colonoscopy for screening compared to those for surveillance (16.7 vs. 3.5% non-adherence, respectively, P < 0.001). An indication of screening in comparison with surveillance was associated with non-adherence [odds ratio (OR) 12.69, 95% CI 4.18-38.51] and multiple cancellations (OR 2.33, 95% CI 1.27-4.31) by multiple regression analysis.
Patients undergoing colonoscopy for CRC screening are significantly less likely to attend their scheduled procedure within a year and have more procedure cancellations than those undergoing surveillance colonoscopy.
相当一部分符合条件的人群未坚持进行结肠镜检查以筛查结直肠癌(CRC)。
确定在CRC筛查和腺瘤性息肉监测人群中,与1年内未坚持和多次取消预定结肠镜检查相关的人口统计学和临床变量。
这是一项观察性队列研究,纳入了2012年1月至2012年9月期间在一家门诊学术三级医疗中心计划接受结肠镜检查以进行CRC筛查或腺瘤性息肉监测的617例连续患者。
总体而言,1年后551例患者(89.3%)坚持进行预定的结肠镜检查,66例(10.7%)未坚持。与接受监测的患者相比,接受结肠镜检查进行筛查的患者未坚持的相对风险为5.42[95%置信区间(CI)2.74 - 10.75](未坚持率分别为16.7%和3.5%,P < 0.001)。通过多因素回归分析,与监测相比,筛查指征与未坚持[比值比(OR)12.69,95%CI 4.18 - 38.51]和多次取消(OR 2.33,95%CI 1.27 - 4.31)相关。
与接受监测结肠镜检查的患者相比,接受CRC筛查结肠镜检查的患者在1年内参加预定检查的可能性显著降低,且检查取消次数更多。